Kaur Gurpreet, Prakash Gaurav, Malhotra Pankaj, Ghai Sandhya, Kaur Sukhpal, Singh Mahender, Kaur Kulbeer
National Institute of Nursing Education, Postgraduate Institute Medical Education and Research, Chandigarh, India.
Department of Internal Medicine, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Int J Yoga. 2018 Sep-Dec;11(3):249-254. doi: 10.4103/ijoy.IJOY_17_18.
Yoga is proven beneficial in improving quality of life among breast cancer survivors receiving chemotherapy, but its effectiveness in lymphoma patients needs to be explored. As chemotherapy-induced neutropenia is very common among lymphoma patients, they are much prone to infections from the environment. Furthermore, trained yoga instructors are not available in every setting, so there is a need to develop home-based yoga program modules for lymphoma patients receiving chemotherapy.
The aim of the study was to explore the feasibility and safety of yogic exercises among lymphoma patients during chemotherapy.
An interventional, single-arm prepost design study was conducted at a tertiary health-care center. Patients suffering from malignant lymphoma (18-65 years) with Eastern Cooperative Oncology Group performance status from 0 to 2, planned to receive chemotherapy were administered a home-based yoga program over a period of 2 months from the start of chemotherapy. The primary outcome variables were retention rate, acceptance rate, safety, and adherence. Health-related quality of life (HRQOL), fatigue level, overall sleep quality, depression, anxiety level, and pain were also assessed.
Descriptive statistics was used to see the feasibility and adherence. The paired -test was used to compare various pre and postintervention outcome measures.
Fourteen patients (median age: 36 years, range13-65 years) of malignant lymphoma were enrolled in the study. Male-to-female ratio was 9:5. Non-Hodgkin's lymphoma patients constituted 64%. The recruitment rate was 93%. Favorable retention (100%), acceptability (97%), adherence (78.6%), and no serious adverse events following yoga practice were reported. Improvement was also found in HRQOL, fatigue, sleep, depression, and anxiety. However, it needs further validation in a randomized study.
Home-based yoga program is safe and feasible among the patients suffering from malignant lymphoma receiving chemotherapy.
事实证明，瑜伽有助于改善接受化疗的乳腺癌幸存者的生活质量，但其对淋巴瘤患者的有效性仍有待探索。由于化疗引起的中性粒细胞减少症在淋巴瘤患者中非常常见，他们极易受到环境感染。此外，并非每个地方都有训练有素的瑜伽教练，因此有必要为接受化疗的淋巴瘤患者开发居家瑜伽项目模块。
本研究旨在探讨化疗期间淋巴瘤患者进行瑜伽练习的可行性和安全性。
在一家三级医疗保健中心进行了一项干预性单臂前后设计研究。患有恶性淋巴瘤（年龄18 - 65岁）、东部肿瘤协作组体能状态为0至2、计划接受化疗的患者，从化疗开始起的2个月内接受居家瑜伽项目。主要结局变量为保留率、接受率、安全性和依从性。还评估了健康相关生活质量（HRQOL）、疲劳程度、总体睡眠质量、抑郁、焦虑水平和疼痛情况。
采用描述性统计来观察可行性和依从性。配对t检验用于比较干预前后的各种结局指标。
14例恶性淋巴瘤患者（中位年龄：36岁，范围13 - 65岁）纳入研究。男女比例为9:5。非霍奇金淋巴瘤患者占64%。招募率为93%。报告显示瑜伽练习后的保留率良好（100%）、可接受性（97%）、依从性（78.6%），且未出现严重不良事件。在健康相关生活质量、疲劳、睡眠（质量）、抑郁和焦虑方面也有改善。然而，这需要在随机研究中进一步验证。
居家瑜伽项目对于接受化疗的恶性淋巴瘤患者是安全可行的。
