口服甜味溶液预防新生儿髋关节检查疼痛的随机对照试验。
Oral sweet solution to prevent pain during neonatal hip examination: a randomised controlled trial.
机构信息
Department of Pediatrics, Faculty of Medicine and Health, Örebro University, Örebro, Sweden.
Faculty of Medicine and Health, School of Health Sciences, Örebro University, Örebro, Sweden.
出版信息
Acta Paediatr. 2019 Apr;108(4):626-629. doi: 10.1111/apa.14588. Epub 2018 Oct 12.
AIM
To determine if oral glucose can have a pain-relieving effect during routine hip examinations in newborn infants.
METHODS
In this randomised controlled study 100 newborn infants undergoing the routine physical examination including the potentially painful hip examination were included between March 2016 and April 2017. Fifty infants were randomised to water (control) and 50 to oral glucose (intervention) before their examination. Pain was assessed using crying time, Astrid Lindgren and Lund Children's Hospital Pain and Stress Assessment Scale (ALPS-Neo) and Visual analogue scale (VAS).
RESULTS
Total crying time (p = 0.006), crying time during the hip examination (p = 0.026), ALPS-Neo (p = 0.004) and VAS (p = 0.006) (when assessed by the physician) were all significantly decreased in the group of infants receiving glucose. VAS assessment made by the parents did not reach statistical significance (p = 0.127).
CONCLUSION
Oral glucose given before the examination has a pain-relieving effect during the hip examination in healthy newborn infants.
目的
确定口服葡萄糖是否能在新生儿常规髋关节检查中缓解疼痛。
方法
本随机对照研究纳入了 2016 年 3 月至 2017 年 4 月期间 100 例行常规体格检查（包括可能引起疼痛的髋关节检查）的新生儿。50 例婴儿在检查前随机分为水（对照组）和口服葡萄糖（干预组）。使用哭泣时间、Astrid Lindgren 和隆德儿童医院疼痛和应激评估量表（ALPS-Neo）和视觉模拟评分（VAS）评估疼痛。
结果
葡萄糖组的总哭泣时间（p=0.006）、髋关节检查时的哭泣时间（p=0.026）、ALPS-Neo（p=0.004）和 VAS（p=0.006）（由医生评估）均显著降低。父母评估的 VAS 无统计学意义（p=0.127）。
结论
在健康新生儿的髋关节检查前给予口服葡萄糖可缓解疼痛。
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