Humphry R C, Parkin J M, Marsh R J
Trans Ophthalmol Soc U K (1962). 1986;105 ( Pt 5):505-9.
The ocular findings in 38 patients infected by the Human T Cell Lymphotropic Virus Type III (HTLV III) are reviewed. Twenty patients were suffering from the Acquired Immunodeficiency Syndrome (AIDS) and 18 from the HTLV III related disease Persistent Generalised Lymphadenopathy (PGL). Cotton wool spots were found in the retinae of 8 patients at some stage of their disease and the prognostic significance of these is discussed. Cytomegalovirus (CMV) Retinitis was an ocular complication in eight of the patients with AIDS. The therapeutic effects of a new anti-viral drug, di-hydroxy propoxymethyl guanine (DHPG), are discussed.
对38例感染人类嗜T淋巴细胞病毒III型(HTLV III)患者的眼部检查结果进行了回顾。20例患有获得性免疫缺陷综合征(AIDS),18例患有与HTLV III相关的疾病——持续性全身性淋巴结病(PGL)。在8例患者病程的某些阶段,视网膜出现了棉絮状斑,并对其预后意义进行了讨论。巨细胞病毒(CMV)视网膜炎是8例AIDS患者的眼部并发症。讨论了一种新型抗病毒药物二羟基丙氧甲基鸟嘌呤(DHPG)的治疗效果。