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用于抗菌伤口敷料的原位静电纺丝碘基纤维网

In Situ Electrospinning Iodine-Based Fibrous Meshes for Antibacterial Wound Dressing.

作者信息

Liu Guo-Sai, Yan Xu, Yan Fang-Fang, Chen Fu-Xing, Hao Long-Yun, Chen Shao-Juan, Lou Tao, Ning Xin, Long Yun-Ze

机构信息

Industrial Research Institute of Nonwovens and Technical Textiles, College of Textiles and Clothing, Qingdao University, Qingdao, 266071, China.

Collaborative Innovation Center for Eco-Textiles of Shandong Province, Qingdao University, Qingdao, 266071, China.

出版信息

Nanoscale Res Lett. 2018 Oct 3;13(1):309. doi: 10.1186/s11671-018-2733-9.

Abstract

For effective application of electrospinning and electrospun fibrous meshes in wound dressing, we have in situ electrospun poly(vinyl pyrrolidone)/iodine (PVP/I), PVP/poly(vinyl pyrrolidone)-iodine (PVPI) complex, and poly(vinyl butyral) (PVB)/PVPI solutions into fibrous membranes by a handheld electrospinning apparatus. The morphologies of the electrospun fibers were examined by SEM, and the hydrophobicity, gas permeability, and antibacterial properties of the as-spun meshes were also investigated. The flexibility and feasibility of in situ electrospinning PVP/I, PVP/PVPI, and PVB/PVPI membranes, as well as the excellent gas permeabilities and antibacterial properties of the as-spun meshes, promised their potential applications in wound healing.

摘要

为了使静电纺丝及电纺纤维网在伤口敷料中得到有效应用,我们使用手持式静电纺丝装置,将聚乙烯吡咯烷酮/碘(PVP/I)、PVP/聚(乙烯基吡咯烷酮)-碘(PVPI)复合物以及聚乙烯醇缩丁醛(PVB)/PVPI溶液原位静电纺制成纤维膜。通过扫描电子显微镜(SEM)检测电纺纤维的形态,并对纺制所得网的疏水性、透气性和抗菌性能进行了研究。原位静电纺丝制备PVP/I、PVP/PVPI和PVB/PVPI膜的灵活性和可行性,以及纺制所得网优异的透气性和抗菌性能,预示了它们在伤口愈合中的潜在应用前景。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c165/6170247/db97debb3571/11671_2018_2733_Fig1_HTML.jpg

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