de Fez Dolores, Luque María José, Matea Lucía, Piñero David P, Camps Vicente J
Department of Optics, Pharmacology and Anatomy, University of Alicante, Alicante, Spain.
Department of Optics, University of Valencia, Valencia, Spain.
Graefes Arch Clin Exp Ophthalmol. 2018 Dec;256(12):2349-2360. doi: 10.1007/s00417-018-4154-y. Epub 2018 Oct 6.
To develop and validate a new iPad-based color vision test (Optopad).
A total of 341 student eyes were enrolled in a first comparative study between Optopad and the Isihara tests. In a second comparative study, Optopad vs. the Farnworth-Munsell test (FM 100H), a total of 66 adult eyes were included. Besides the agreement between tests, the correlation between FM 100H and Optopad outcomes were investigated. Multiple regression analysis was used to predict the total error score (TES) from contrast thresholds measured with the Optopad test.
The Ishihara and Optopad tests detected the same anomalous patients. Concerning FM 100H vs. Optopad, 10 subjects were diagnosed as anomalous with both tests, 3 mild anomalous cases based on TES were classified as normal with Optopad, and 2 anomalous subjects based on Optopad test showed normal TES values. Statistically significant correlations of TES and partial error red-green (PTESRG) with thresholds measured with the red-green Optopad stimuli were found. A multiple quadratic regression model was obtained relating TES and chromatic contrast values from Optopad (R = 0.855), with only 13 cases showing residuals of ≥ 25 units.
The design and implementation of a chromatic contrast discrimination test has been carried out, with promising clinical results. This test seems to provide comparable outcomes to those obtained with Ishihara and FM 100H tests.
开发并验证一种新的基于iPad的色觉测试（Optopad）。
在Optopad与石原氏测试的首次比较研究中，共纳入了341名学生的眼睛。在第二次比较研究中，Optopad与 Farnworth-Munsell测试（FM 100H），共纳入了66名成年人的眼睛。除了测试之间的一致性外，还研究了FM 100H与Optopad结果之间的相关性。使用多元回归分析从Optopad测试测量的对比度阈值预测总误差分数（TES）。
石原氏测试和Optopad测试检测出相同的异常患者。关于FM 100H与Optopad，10名受试者在两种测试中均被诊断为异常，3例基于TES的轻度异常病例在Optopad测试中被分类为正常，2例基于Optopad测试的异常受试者显示TES值正常。发现TES和部分红绿误差（PTESRG）与红绿Optopad刺激测量的阈值之间存在统计学上的显著相关性。获得了一个多元二次回归模型，该模型将TES与Optopad的色度对比度值相关联（R = 0.855），只有13例显示残差≥25个单位。
已经开展了一项色度对比度辨别测试的设计与实施，临床结果令人满意。该测试似乎能提供与石原氏测试和FM 100H测试相当的结果。
