自发性和诱发性便秘中的肠易激型症状。
Irritable bowel-type symptoms in spontaneous and induced constipation.
作者信息
Marcus S N, Heaton K W
出版信息
Gut. 1987 Feb;28(2):156-9. doi: 10.1136/gut.28.2.156.
The prevalence and severity of irritable bowel symptoms was assessed by systematic questioning in 44 constipated volunteers, most of whom had documented slow intestinal transit. All but two had one or more of the following: passage of mucus, rectal dissatisfaction, bloating, and abdominal pain relieved by defecation. All the symptoms were more prevalent than in 17 normal volunteers or in 301 apparently healthy people studied previously. When 12 normal subjects were made constipated with loperamide all developed one or more irritable bowel symptoms. When 24 constipated subjects received effective laxative treatment the prevalence and severity of these symptoms fell markedly. The findings suggest that in some subjects the slowing down of intestinal transit is associated with irritable bowel symptoms.
通过系统询问，对44名便秘志愿者的肠易激症状的患病率和严重程度进行了评估，其中大多数人有肠道传输缓慢的记录。除两人外，所有人都有以下一种或多种症状：排出黏液、直肠不适、腹胀以及排便后缓解的腹痛。所有这些症状比17名正常志愿者或先前研究的301名明显健康的人更普遍。当12名正常受试者用洛哌丁胺导致便秘时，所有人都出现了一种或多种肠易激症状。当24名便秘受试者接受有效的泻药治疗时，这些症状的患病率和严重程度明显下降。这些发现表明，在一些受试者中，肠道传输减慢与肠易激症状有关。
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