评价一种用于单纯疱疹病毒的快速乳胶玻片凝集试验作为标本筛查和培养鉴定方法的效果。
Evaluation of a rapid latex slide agglutination test for herpes simplex virus as a specimen screen and culture identification method.
作者信息
Halstead D C, Beckwith D G, Sautter R L, Plosila L, Schneck K A
出版信息
J Clin Microbiol. 1987 May;25(5):936-7. doi: 10.1128/jcm.25.5.936-937.1987.
Abstract
A total of 449 clinical specimens and 199 culture fluids were tested using the Virogen Herpes Slide Test (Wampole Laboratories, Div. Carter-Wallace, Inc., Cranbury, N.J.), a rapid latex agglutination procedure. The results were compared with those obtained with isolation of herpes simplex virus in cell culture followed by identification using immunoperoxidase or fluorescent reagents. The sensitivity, specificity, and positive and negative predictive values of the direct test were 49.7, 93.4, 96.0, and 37.1%, respectively. The sensitivity and specificity of the latex agglutination test for culture confirmation were 75.9 and 100%, respectively.
摘要
使用Virogen疱疹玻片试验（Wampole实验室，卡特-华莱士公司分部，新泽西州克兰伯里）这一快速乳胶凝集程序，对总共449份临床标本和199份培养液进行了检测。将结果与通过细胞培养分离单纯疱疹病毒，随后使用免疫过氧化物酶或荧光试剂进行鉴定所获得的结果进行比较。直接检测的敏感性、特异性、阳性预测值和阴性预测值分别为49.7%、93.4%、96.0%和37.1%。用于培养确认的乳胶凝集试验的敏感性和特异性分别为75.9%和100%。
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