School of Engineering, Sun Yat-Sen University, Guangzhou 510006, China.
J Biomed Nanotechnol. 2012 Feb;8(1):1-9. doi: 10.1166/jbn.2012.1360.
Electrospinning is an exciting technique attracting more and more attention as a potential solution to the current challenges in the field of tissue engineering. This technique can be used to produce fibrous scaffolds with excellent biocompatibility and biodegradability, as well as suitable micro-/nanostructure to induce desired cellular activities and to guide tissue regeneration. In order to develop electrospun fibrous scaffolds for these applications, different biocompatible materials including natural polymers, synthetic polymers and inorganic substances and preparations have been used to fabricate electrospun fibers with different structures and morphologies. This review briefly describes the development of the technique, focusing on several typically electrospun materials, surface modification of electrospun fibers, and current applications in tissue engineering.
静电纺丝是一种令人兴奋的技术，作为解决组织工程领域当前挑战的潜在解决方案，越来越受到关注。该技术可用于生产具有优异生物相容性和可生物降解性的纤维支架，以及合适的微/纳米结构，以诱导所需的细胞活动并指导组织再生。为了开发用于这些应用的静电纺纤维支架，已经使用了不同的生物相容性材料，包括天然聚合物、合成聚合物和无机物质和制剂，以制造具有不同结构和形态的静电纺纤维。本文简要介绍了该技术的发展，重点介绍了几种典型的静电纺丝材料、静电纺丝纤维的表面改性以及在组织工程中的应用。
