Nucleic Acids Res. 2019 Jan 8;47(D1):D8-D14. doi: 10.1093/nar/gky993.
The BIG Data Center at Beijing Institute of Genomics (BIG) of the Chinese Academy of Sciences provides a suite of database resources in support of worldwide research activities in both academia and industry. With the vast amounts of multi-omics data generated at unprecedented scales and rates, the BIG Data Center is continually expanding, updating and enriching its core database resources through big data integration and value-added curation. Resources with significant updates in the past year include BioProject (a biological project library), BioSample (a biological sample library), Genome Sequence Archive (GSA, a data repository for archiving raw sequence reads), Genome Warehouse (GWH, a centralized resource housing genome-scale data), Genome Variation Map (GVM, a public repository of genome variations), Science Wikis (a catalog of biological knowledge wikis for community annotations) and IC4R (Information Commons for Rice). Newly released resources include EWAS Atlas (a knowledgebase of epigenome-wide association studies), iDog (an integrated omics data resource for dog) and RNA editing resources (for editome-disease associations and plant RNA editosome, respectively). To promote biodiversity and health big data sharing around the world, the Open Biodiversity and Health Big Data (BHBD) initiative is introduced. All of these resources are publicly accessible at http://bigd.big.ac.cn.
中国科学院北京基因组研究所（BIG）的大数据中心提供了一系列数据库资源，以支持学术界和工业界的全球研究活动。随着多组学数据以空前的规模和速度产生，BIG 数据中心通过大数据整合和增值策展不断扩展、更新和丰富其核心数据库资源。在过去一年中进行了重大更新的资源包括 BioProject（生物项目库）、BioSample（生物样本库）、Genome Sequence Archive（GSA，用于存储原始序列读取的数据库）、Genome Warehouse（GWH，用于存储基因组规模数据的集中资源）、Genome Variation Map（GVM，用于发布基因组变异的公共存储库）、Science Wikis（用于生物知识社区注释的生物知识维基目录）和 IC4R（水稻信息公共领域）。新发布的资源包括 EWAS Atlas（全基因组关联研究的知识库）、iDog（狗的综合组学数据资源）和 RNA 编辑资源（分别用于编辑组疾病关联和植物 RNA 编辑体）。为了促进全球生物多样性和健康大数据的共享，推出了开放生物多样性和健康大数据（BHBD）倡议。所有这些资源都可以在 http://bigd.big.ac.cn 上公开访问。
