• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

分析树皮中原花青素的分布并评估其体外抗氧化和抗糖尿病潜力。

Analytical Profiling of Proanthocyanidins from Bark and In Vitro Assessment of Antioxidant and Antidiabetic Potential.

机构信息

Jiangsu Key Lab for the Chemistry and Utilization of Agro-Forest Biomass, College of Chemical Engineering, Nanjing Forestry University, Nanjing 210037, China.

Food Bioprocessing and Nutrition Sciences Department, Plants for Human Health Institute, North Carolina State University, North Carolina Research Campus, Kannapolis, NC 28081, USA.

出版信息

Molecules. 2018 Nov 6;23(11):2891. doi: 10.3390/molecules23112891.

DOI:10.3390/molecules23112891
PMID:30404154
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6278516/
Abstract

The proanthocyanidins from ethanol extracts (80%, /) of () bark on chemical-based and cellular antioxidant activity assays as well as carbolytic enzyme inhibitory activities were studied. About 77% of oligomeric proanthocyanidins in ethanol extracts of bark were found by using normal-phase HPLC. In addition, HPLC-ESI-TOF/MS and MALDI-TOF/TOF MS analyses indicated that proanthocyanidins from bark exhibited with a degree of polymerization ranging from 1 to 11. These results of combined antioxidant activity assays, as well as carbolytic enzyme inhibitory activities of proanthocyanidins from bark, indicated an encouraging antioxidant capacity for the high polyphenol content and a potential for use as alternative drugs for lowering the glycemic response.

摘要

从 ()树皮的乙醇提取物(80%/)中提取的原花青素在基于化学和细胞的抗氧化活性测定以及裂解酶抑制活性方面进行了研究。通过使用正相 HPLC,发现 树皮乙醇提取物中有约 77%的低聚原花青素。此外,HPLC-ESI-TOF/MS 和 MALDI-TOF/TOF MS 分析表明,来自 树皮的原花青素具有聚合度从 1 到 11 的范围。这些综合抗氧化活性测定以及 树皮中原花青素的裂解酶抑制活性的结果表明,由于高多酚含量,其具有令人鼓舞的抗氧化能力,并且可能可作为降低血糖反应的替代药物。

相似文献

1
Analytical Profiling of Proanthocyanidins from Bark and In Vitro Assessment of Antioxidant and Antidiabetic Potential.分析树皮中原花青素的分布并评估其体外抗氧化和抗糖尿病潜力。
Molecules. 2018 Nov 6;23(11):2891. doi: 10.3390/molecules23112891.
2
Effects of In Vitro Digestion on the Content and Biological Activity of Polyphenols from Bark.体外消化对树皮中多酚含量和生物活性的影响。
Molecules. 2018 Jul 20;23(7):1804. doi: 10.3390/molecules23071804.
3
Characterization of the α-Amylase Inhibitory Activity of Oligomeric Proanthocyanidins from Acacia mearnsii Bark Extract.黑荆树皮提取物中低聚原花青素的α-淀粉酶抑制活性表征
Nat Prod Commun. 2016 Dec;11(12):1851-1854.
4
Polyphenols isolated from Acacia mearnsii bark with anti-inflammatory and carbolytic enzyme inhibitory activities.从金合欢树皮中分离得到的具有抗炎和脱羧酶抑制活性的多酚。
Chin J Nat Med. 2017 Nov;15(11):816-824. doi: 10.1016/S1875-5364(18)30015-3.
5
Characterisation and biological activities of proanthocyanidins from the barks of Pinus massonian and Acacia mearnsii.马尾松和金合欢树皮中原花青素的特性及生物活性研究。
Nat Prod Res. 2010 Apr;24(6):590-8. doi: 10.1080/14786410903194472.
6
Tannins from Acacia mearnsii De Wild. Bark: Tannin Determination and Biological Activities.金合欢单宁的提取及其生物活性研究
Molecules. 2018 Apr 5;23(4):837. doi: 10.3390/molecules23040837.
7
α-Amylase and lipase inhibitory activity and structural characterization of acacia bark proanthocyanidins.阿拉伯树胶原花青素的α-淀粉酶和脂肪酶抑制活性及结构特征。
J Nat Prod. 2011 Feb 25;74(2):119-28. doi: 10.1021/np100372t. Epub 2010 Dec 30.
8
Antioxidant activities of fractions of polymeric procyanidins from stem bark of Acacia confusa.台湾相思树茎皮中聚合原花青素各组分的抗氧化活性
Int J Mol Sci. 2011 Feb 15;12(2):1146-60. doi: 10.3390/ijms12021146.
9
Analysis of commercial proanthocyanidins. Part 5: A high resolution mass spectrometry investigation of the chemical composition of sulfited wattle (Acacia mearnsii De Wild.) bark extract.分析商用原花青素。第 5 部分:亚硫酸化金合欢(Acacia mearnsii De Wild.)树皮提取物化学成分的高分辨质谱研究。
Phytochemistry. 2019 Jun;162:109-120. doi: 10.1016/j.phytochem.2018.12.008. Epub 2019 Mar 15.
10
Analysis of commercial proanthocyanidins. Part 3: the chemical composition of wattle (Acacia mearnsii) bark extract.分析商用原花青素。第 3 部分:金合欢树皮提取物的化学成分。
Phytochemistry. 2012 Nov;83:153-67. doi: 10.1016/j.phytochem.2012.07.012. Epub 2012 Aug 20.

引用本文的文献

1
Optimization of Ultrasonic-Enzyme Synergistic Extraction of Proanthocyanidins from Jujube: Purification, Characterization, and Bioactivity Study.枣中原花青素的超声-酶协同提取优化:纯化、表征及生物活性研究
Molecules. 2025 Jan 31;30(3):619. doi: 10.3390/molecules30030619.
2
Oligomeric Proanthocyanidins: An Updated Review of Their Natural Sources, Synthesis, and Potentials.低聚原花青素:其天然来源、合成及潜力的最新综述
Antioxidants (Basel). 2023 Apr 26;12(5):1004. doi: 10.3390/antiox12051004.
3
Regulation of Plant Tannin Synthesis in Crop Species.

本文引用的文献

1
Effects of In Vitro Digestion on the Content and Biological Activity of Polyphenols from Bark.体外消化对树皮中多酚含量和生物活性的影响。
Molecules. 2018 Jul 20;23(7):1804. doi: 10.3390/molecules23071804.
2
Antioxidant activity, total phenolics and flavonoids contents: Should we ban in vitro screening methods?抗氧化活性、总酚和类黄酮含量:我们是否应该禁止体外筛选方法?
Food Chem. 2018 Oct 30;264:471-475. doi: 10.1016/j.foodchem.2018.04.012. Epub 2018 Apr 11.
3
Tannins from Acacia mearnsii De Wild. Bark: Tannin Determination and Biological Activities.
作物物种中植物单宁合成的调控
Front Genet. 2022 May 2;13:870976. doi: 10.3389/fgene.2022.870976. eCollection 2022.
4
Molecular Mechanistic Pathways Targeted by Natural Antioxidants in the Prevention and Treatment of Chronic Kidney Disease.天然抗氧化剂在慢性肾脏病防治中靶向的分子机制途径
Antioxidants (Basel). 2021 Dec 22;11(1):15. doi: 10.3390/antiox11010015.
5
A Narrative Review of Human Clinical Trials on the Impact of Phenolic-Rich Plant Extracts on Prediabetes and Its Subgroups.富含酚类植物提取物对糖尿病前期及其亚组影响的人体临床试验的叙述性综述
Nutrients. 2021 Oct 22;13(11):3733. doi: 10.3390/nu13113733.
6
Advances in Biosynthesis and Biological Functions of Proanthocyanidins in Horticultural Plants.园艺植物中原花青素的生物合成及生物学功能研究进展
Foods. 2020 Nov 30;9(12):1774. doi: 10.3390/foods9121774.
7
Unravelling the Biological Potential of Bark Extracts.揭示树皮提取物的生物潜力
Antioxidants (Basel). 2020 Apr 20;9(4):334. doi: 10.3390/antiox9040334.
金合欢单宁的提取及其生物活性研究
Molecules. 2018 Apr 5;23(4):837. doi: 10.3390/molecules23040837.
4
Polyphenols isolated from Acacia mearnsii bark with anti-inflammatory and carbolytic enzyme inhibitory activities.从金合欢树皮中分离得到的具有抗炎和脱羧酶抑制活性的多酚。
Chin J Nat Med. 2017 Nov;15(11):816-824. doi: 10.1016/S1875-5364(18)30015-3.
5
Impact of in vitro simulated digestion on the potential health benefits of proanthocyanidins from Choerospondias axillaris peels.体外模拟消化对南酸枣果皮原花青素潜在健康益处的影响。
Food Res Int. 2015 Dec;78:378-387. doi: 10.1016/j.foodres.2015.09.004. Epub 2015 Sep 10.
6
Phytochemical Characterization and Anti-inflammatory Properties of Acacia mearnsii Leaves.黑荆树叶的植物化学特征及抗炎特性
Nat Prod Commun. 2016 May;11(5):649-53.
7
Antioxidant activity of proanthocyanidins-rich fractions from Choerospondias axillaris peels using a combination of chemical-based methods and cellular-based assay.采用基于化学的方法和基于细胞的分析相结合的方式,对南酸枣果皮中富含原花青素的组分进行抗氧化活性研究。
Food Chem. 2016 Oct 1;208:309-17. doi: 10.1016/j.foodchem.2016.04.012. Epub 2016 Apr 6.
8
High-Molecular-Weight Proanthocyanidins in Foods: Overcoming Analytical Challenges in Pursuit of Novel Dietary Bioactive Components.食品中的高分子量原花青素:克服分析挑战,追求新型膳食生物活性成分。
Annu Rev Food Sci Technol. 2016;7:43-64. doi: 10.1146/annurev-food-022814-015604. Epub 2015 Dec 21.
9
α-Glucosidase Inhibition and Antihyperglycemic Activity of Phenolics from the Flowers of Edgeworthia gardneri.结香花中酚类物质的α-葡萄糖苷酶抑制作用及降血糖活性
J Agric Food Chem. 2015 Sep 23;63(37):8162-9. doi: 10.1021/acs.jafc.5b03081. Epub 2015 Sep 15.
10
In vitro digestion combined with cellular assay to determine the antioxidant activity in Chinese bayberry (Myrica rubra Sieb. et Zucc.) fruits: a comparison with traditional methods.采用体外消化结合细胞检测法测定杨梅(Myrica rubra Sieb. et Zucc.)果实的抗氧化活性:与传统方法的比较。
Food Chem. 2014 Mar 1;146:363-70. doi: 10.1016/j.foodchem.2013.09.071. Epub 2013 Sep 21.