Zhou Kequan
Department of Nutrition & Food Science, Wayne State University, Detroit, MI 48202, USA.
J Funct Foods. 2017 Jun;33:194-201. doi: 10.1016/j.jff.2017.03.045. Epub 2017 Mar 29.
is a mucin-degrading bacterium commonly found in human gut. has been inversely associated with obesity, diabetes, inflammation, and metabolic disorders. Due to its highly promising probiotic activities against obesity and diabetes, has drawn intensive interest for research and development in recent years. A number of human and animal studies have shown that the abundance of in the gut can be enhanced through dietary interventions. The present review focuses on evidence-based dietary strategies of improving abundance in the gut by critically appraising up-to-date available human and animal intervention studies on growth and their impact on risk factors of obesity and diabetes. Their potential mechanisms in promoting are also discussed along with the discussions of mechanism of action for to exert probiotic functions.
是一种常见于人类肠道的粘蛋白降解细菌。它与肥胖、糖尿病、炎症和代谢紊乱呈负相关。由于其对肥胖和糖尿病具有极具前景的益生菌活性,近年来引起了广泛的研究和开发兴趣。多项人体和动物研究表明,通过饮食干预可以提高肠道中该细菌的丰度。本综述通过批判性评估有关该细菌生长及其对肥胖和糖尿病风险因素影响的最新人体和动物干预研究,重点关注基于证据的提高肠道中该细菌丰度的饮食策略。还讨论了促进该细菌生长的潜在机制以及该细菌发挥益生菌功能的作用机制。