European Molecular Biology Laboratory, European Bioinformatics Institute (EMBL-EBI), Wellcome Genome Campus, Hinxton, Cambridge CB10 1SD, UK.
Nucleic Acids Res. 2019 Jan 8;47(D1):D15-D22. doi: 10.1093/nar/gky1124.
The European Bioinformatics Institute (https://www.ebi.ac.uk/) archives, curates and analyses life sciences data produced by researchers throughout the world, and makes these data available for re-use globally (https://www.ebi.ac.uk/). Data volumes continue to grow exponentially: total raw storage capacity now exceeds 160 petabytes, and we manage these increasing data flows while maintaining the quality of our services. This year we have improved the efficiency of our computational infrastructure and doubled the bandwidth of our connection to the worldwide web. We report two new data resources, the Single Cell Expression Atlas (https://www.ebi.ac.uk/gxa/sc/), which is a component of the Expression Atlas; and the PDBe-Knowledgebase (https://www.ebi.ac.uk/pdbe/pdbe-kb), which collates functional annotations and predictions for structure data in the Protein Data Bank. Additionally, Europe PMC (http://europepmc.org/) has added preprint abstracts to its search results, supplementing results from peer-reviewed publications. EMBL-EBI maintains over 150 analytical bioinformatics tools that complement our data resources. We make these tools available for users through a web interface as well as programmatically using application programming interfaces, whilst ensuring the latest versions are available for our users. Our training team, with support from all of our staff, continued to provide on-site, off-site and web-based training opportunities for thousands of researchers worldwide this year.
欧洲生物信息学研究所（https://www.ebi.ac.uk/）负责归档、管理和分析全球研究人员生成的生命科学数据，并在全球范围内提供这些数据供重复使用（https://www.ebi.ac.uk/）。数据量持续呈指数级增长：总原始存储容量现在超过 1600 PB，我们在管理这些不断增长的数据流量的同时，还保持着服务质量。今年，我们提高了计算基础设施的效率，并将与万维网的连接带宽提高了一倍。我们报告了两个新的数据资源，单细胞表达图谱（https://www.ebi.ac.uk/gxa/sc/），它是表达图谱的一个组成部分；以及 PDBe-知识库（https://www.ebi.ac.uk/pdbe/pdbe-kb），它汇集了蛋白质数据库中结构数据的功能注释和预测。此外，欧洲 PMC（http://europepmc.org/）在其搜索结果中添加了预印本摘要，补充了同行评议出版物的结果。EMBL-EBI 维护着 150 多个分析生物信息学工具，这些工具补充了我们的数据资源。我们通过 Web 界面以及使用应用程序编程接口为用户提供这些工具，同时确保我们的用户可以使用最新版本。今年，我们的培训团队在全体员工的支持下，继续为全球数千名研究人员提供现场、场外和基于网络的培训机会。
