Li Chun-Xia, Kempf Doty J, Tong Frank C, Yan Yumei, Xu Zhengfeng, Connor-Stroud Fawn R, Ford Byron D, Howell Leonard L, Zhang Xiaodong
Yerkes National Primate Research Center, Emory University, Atlanta, Georgia, USA.
Departments of Radiology and Psychiatry and Behavioral Sciences, School of Medicine, Emory University, Atlanta, Georgia, USA.
Comp Med. 2018 Dec 1;68(6):496-502. doi: 10.30802/AALAS-CM-18-000004. Epub 2018 Nov 28.
An adult rhesus macaque developed seizures after the induction of ischemic stroke. Initially, on the day of surgery, a focal ischemic lesion was present exclusively in the right caudate nucleus. By 48 h after stroke induction, the lesion had extended into the putamen, when a seizure was observed. Our report highlights the temporal changes in infarction of unilateral basal ganglia after acute stroke and the accompanying clinical symptoms. This unusual case may provide additional information regarding the involvement of the basal ganglia in seizures, given that prior case reports and studies usually have not described the temporal and spatial evolution of the lesion before clinical symptoms emerge.
一只成年恒河猴在诱发缺血性中风后出现癫痫发作。最初，在手术当天，右侧尾状核单独出现局灶性缺血性病变。中风诱发后48小时，病变扩展到壳核，此时观察到癫痫发作。我们的报告强调了急性中风后单侧基底神经节梗死的时间变化以及伴随的临床症状。鉴于之前的病例报告和研究通常没有描述临床症状出现前病变的时间和空间演变情况，这个不寻常的病例可能会提供有关基底神经节与癫痫发作关系的更多信息。
