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中国卒中负担:一项全国范围内基于人群的流行病学调查结果。

The burden of stroke in China: Results from a nationwide population-based epidemiological survey.

机构信息

Department of Neuroepidemiology, Beijing Neurosurgical Institute, Capital Medical University, Beijing, China.

Beijing Municipal Key Laboratory of Clinical Epidemiology, Beijing, China.

出版信息

PLoS One. 2018 Dec 6;13(12):e0208398. doi: 10.1371/journal.pone.0208398. eCollection 2018.

DOI:10.1371/journal.pone.0208398
PMID:30521583
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6283556/
Abstract

Stroke is a serious threat to human health that often leads to severe complications, and currently ranks first as leading cause of death in China. However, reliable data on stroke burden in China in the 21st century are lacking. We used the data from NESS-China (National Epidemiological Survey of Stroke in China) for assessing the adverse health effects of stroke in Chinese population. We carried out inter-regional comparative study in order to obtain regular burden related characteristics of stroke in China, as measured by YLLs (years of life lost due to premature mortality), YLDs (years lived with disability) and DALYs (disability adjusted life years). Amongst the nationwide population of 596,536 individuals of all ages in 2013, the YLLs for stroke was 1748, the YLDs was 262, and the DALYs was 2010(per 100,000). The gender subtype analysis of DALYs was 2171(male) and 1848(female). The YLLs, YLDs and DALYs in rural areas were higher compared to urban areas. Among the 18 age groups, the highest YLLs was observed in ≥ 80 years old group. The impact of stroke on Chinese population is more severe compared to the global average levels. Stroke results as the main cause of YLLs in China, while there is no significant difference for the YLDs. Nevertheless, DALYs caused by stroke rank 3th in global epidemiologic study territories, 1st in China.

摘要

中风是对人类健康的严重威胁,常导致严重并发症,目前是中国的首要死因。然而,目前缺乏 21 世纪中国中风负担的可靠数据。我们使用了NESS-China(中国国家卒中流行病学调查)的数据,以评估中风对中国人群的不良健康影响。我们进行了跨区域比较研究,以获得中国中风相关负担的规律特征,其指标为 YLL(因过早死亡导致的生命损失年)、YLD(伤残生命年)和 DALY(残疾调整生命年)。在 2013 年全国 596536 名各年龄段人群中,中风的 YLL 为 1748 年,YLD 为 262 年,DALY 为 2010 年(每 10 万人)。DALY 的性别亚组分析为 2171(男性)和 1848(女性)。农村地区的 YLL、YLD 和 DALY 均高于城市地区。在 18 个年龄组中,≥80 岁年龄组的 YLL 最高。与全球平均水平相比,中风对中国人口的影响更为严重。中风是中国 YLL 的主要原因,而 YLD 则没有显著差异。然而,在全球流行病学研究领域中,中风导致的 DALY 排名第三,在中国则排名第一。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/50e0/6283556/3e395d82be51/pone.0208398.g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/50e0/6283556/90d1a77046a1/pone.0208398.g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/50e0/6283556/3e395d82be51/pone.0208398.g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/50e0/6283556/90d1a77046a1/pone.0208398.g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/50e0/6283556/3e395d82be51/pone.0208398.g002.jpg

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