Food Chemistry and Molecular Cancer Biology Lab, Department of Animal Health and Management, Science Campus, Alagappa University, Karaikudi 630003, India.
Food Chemistry and Molecular Cancer Biology Lab, Department of Animal Health and Management, Science Campus, Alagappa University, Karaikudi 630003, India.
Spectrochim Acta A Mol Biomol Spectrosc. 2019 Mar 15;211:94-99. doi: 10.1016/j.saa.2018.11.047. Epub 2018 Nov 19.
In recent era, the interest on inorganic nanoparticles is augmenting due to their engrossing and uncanny properties. Among them, platinum nanoparticles (PtNPs) are highly remarkable owing to their intrinsic physicochemical and biological properties making them an effective candidate towards catalytic and biomedical applications. Nevertheless, conventional physical and chemical methodologies of PtNPs synthesis are among the most prevalent protocols to synthesize PtNPs of desired shape and size. However, the above methods create notable concern to health and environment due to the use of harsh and toxic chemicals as well as violent reaction conditions. Hence, an economic, eco-friendly, non-toxic and sustainable route for the synthesis of PtNPs is the need of the hour to circumvent the shortcomings associated with conventional methodologies. In this aspect, the approach of green synthesis has lightened up the way for the environmentally benign synthesis of PtNPs. Interestingly, this review focuses chiefly on the green synthesis of PtNPs from various biological entities such as microorganisms, plants, seaweeds and other innovative miscellaneous protocols. Furthermore, it also summarizes the potential biomedical applications of PtNPs especially as an antibacterial agent and their role as nanomedicine. Overall, the emerging biogenic synthesis of PtNPs makes it feasible to foresee more promising biomedical outcomes in the upcoming future.
在最近的时代,由于无机纳米粒子引人入胜和奇特的性质,人们对它们的兴趣日益增加。其中,铂纳米粒子(PtNPs)因其固有物理化学和生物性质而备受关注,使其成为催化和生物医学应用的有效候选物。然而,PtNPs 的传统物理和化学合成方法是合成所需形状和尺寸的 PtNPs 的最常见方法。然而,由于使用了苛刻和有毒的化学物质以及剧烈的反应条件,上述方法对健康和环境造成了显著的关注。因此,需要一种经济、环保、无毒和可持续的方法来合成 PtNPs,以规避与传统方法相关的缺点。在这方面,绿色合成方法为 PtNPs 的环境友好合成开辟了道路。有趣的是,本综述主要关注从各种生物实体(如微生物、植物、海藻和其他创新的混合协议)中绿色合成 PtNPs。此外,它还总结了 PtNPs 的潜在生物医学应用,特别是作为一种抗菌剂及其作为纳米医学的作用。总的来说,新兴的生物合成 PtNPs 使得在未来可以预见更多有前途的生物医学成果。