Timmer Tiffany C, de Groot Rosa, Habets Karin, Merz Eva-Maria, Prinsze Femmeke J, Atsma Femke, de Kort Wim L A M, van den Hurk Katja
Department of Donor Medicine Research - Donor Studies, Sanquin Research, Amsterdam, The Netherlands.
Department of Public Health, Landsteiner Laboratory, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.
Vox Sang. 2019 Feb;114(2):117-128. doi: 10.1111/vox.12731. Epub 2018 Dec 27.
More insight into donor health and behaviour may contribute to more efficient and focused strategies regarding donor care and management. Donor InSight (DIS) is a Dutch cohort study of blood and plasma donors. We aimed to outline the objectives and methods of DIS, describe the cohort, and compare it to the active Dutch donor population.
In 2007-2009 (DIS-I, n = 31 338) and 2012-2013 (DIS-II, 34 826, of whom 22 132 also participated in DIS-I) questionnaire data on demographics, donation, lifestyle, family composition, health and disease were collected. A second follow-up (DIS-III, n = 3046), including donors with differing haemoglobin trajectories, was completed in 2015-2016. DIS-III includes data on genetic determinants, iron and red cell indices. Representativeness of the DIS-I sample for the entire Dutch donor population was assessed by comparing characteristics of both.
Donor InSight was initially set up because of a need for more detailed information and evidence as a basis for decision-making in blood banks. DIS-I sample is comparable to the total Dutch donor population in terms of age, body mass index, haemoglobin level, blood pressure, blood type and donation behaviour.
Donor InSight is a cohort study representative of the Dutch donor population. It provides evidence to support evidence-based decision making.
深入了解献血者的健康状况和行为，可能有助于制定更高效、更具针对性的献血者护理与管理策略。“献血者洞察”（DIS）是一项针对荷兰血液和血浆捐献者的队列研究。我们旨在概述DIS的目标和方法，描述该队列，并将其与活跃的荷兰献血者群体进行比较。
在2007 - 2009年（DIS - I，n = 31338）和2012 - 2013年（DIS - II，34826人，其中22132人也参与了DIS - I），收集了有关人口统计学、献血情况、生活方式、家庭构成、健康和疾病的问卷数据。2015 - 2016年完成了第二次随访（DIS - III，n = 3046），包括血红蛋白轨迹不同的献血者。DIS - III包括基因决定因素、铁和红细胞指数的数据。通过比较两者的特征来评估DIS - I样本对整个荷兰献血者群体的代表性。
设立“献血者洞察”研究最初是因为血库决策需要更详细的信息和证据。DIS - I样本在年龄、体重指数、血红蛋白水平、血压、血型和献血行为方面与荷兰献血者总群体相当。
“献血者洞察”是一项代表荷兰献血者群体的队列研究。它为支持循证决策提供了证据。
