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在家猫中鉴定出一种新型细小病毒。

Identification of a novel parvovirus in domestic cats.

机构信息

Department of Veterinary Medicine, University of Bari, Valenzano, Italy.

Faculty of Veterinary Medicine, University of Teramo, Teramo, Italy.

出版信息

Vet Microbiol. 2019 Jan;228:246-251. doi: 10.1016/j.vetmic.2018.12.006. Epub 2018 Dec 11.

DOI:10.1016/j.vetmic.2018.12.006
PMID:30593374
Abstract

A novel protoparvovirus species was identified in domestic cats. The virus was distantly related to the well-known feline (feline panleukopenia virus) and canine (canine parvovirus type 2) parvoviruses, sharing low nucleotide identities in the capsid protein 2 (less than 43%). The virus was genetically similar (100% at the nucleotide level) to a newly identified canine protoparvovirus, genetically related to human bufaviruses. The feline bufavirus appeared as a common element of the feline virome, especially in juvenile cats, with an overall prevalence of 9.2%. The virus was more common in respiratory samples (9.5%-12.2%) than in enteric samples of cats (2.2%). The role of bufaviruses in the etiology of feline respiratory disease complex, either as a primary or a secondary agents, should be defined.

摘要

一种新型的细小病毒属病毒在宠物猫中被鉴定出来。该病毒与众所周知的猫泛白细胞减少症病毒(feline panleukopenia virus)和犬细小病毒 2 型(canine parvovirus type 2)亲缘关系较远,衣壳蛋白 2 区的核苷酸同源性较低(<43%)。该病毒与一种新鉴定的犬细小病毒属病毒在遗传上相似(核苷酸水平上为 100%),与人类 bufaviruses 相关。猫源 bufavirus 是猫病毒组的常见成分,尤其是在幼猫中,总体流行率为 9.2%。该病毒在呼吸道样本(9.5%-12.2%)中的检出率高于肠道样本(2.2%)。bufaviruses 是否在猫呼吸道疾病的病因学中起作用,无论是作为主要还是次要因素,都需要进一步确定。

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