Terpenes and lignans from the roots of L.

Phytochemical investigation of the roots of L. resulted in the isolation of ten terpenes and sixteen lignans, including a new triterpene saponin, officinoterpenoside E () and twenty-five known compounds (). All compounds were firstly isolated from except , , , . The structures of these compounds were determined by 1 D and 2 D NMR spectra referring to the literatures, together with high-resolution mass spectrometric analysis. All compounds were evaluated for the cytotoxicity against three cancer cell lines (HepG2, Hela, and MCF-7) . The results showed that compounds , , , and exhibited moderate cytotoxicity against HepG2, Hela and MCF-7 cells with IC values in the range of 16.8 ± 1.7 to 29.1 ± 1.9 μM. Therefore, these terpenoids and lignans may have potential biological activity, and also seemed to be of great chemotaxonomic value for .