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嗜中性血管反应。

Neutrophilic vascular reactions.

作者信息

Jorizzo J L, Solomon A R, Zanolli M D, Leshin B

机构信息

Department of Dermatology, Bowman Gray School of Medicine of Wake Forest University, Winston-Salem, NC 27103.

出版信息

J Am Acad Dermatol. 1988 Dec;19(6):983-1005. doi: 10.1016/s0190-9622(88)70264-9.

Abstract

Dermatologic diseases are classified most commonly by morphology, by pathogenesis, or by etiology. Nontraditional classifications may be useful in terms of providing a reassessment of traditional views about disease interrelationships. This review of dermatoses characterized by neutrophilic infiltrates and dermal vessel changes reveals evidence suggesting that these dermatoses result from immune complex-mediated, neutrophil-induced dermal vessel damage. Therapeutic approaches to these heretofore unlinked dermatoses are remarkably similar.

摘要

皮肤病最常见的分类方式是依据形态学、发病机制或病因。非传统分类在重新评估关于疾病相互关系的传统观点方面可能会有所帮助。这篇对以嗜中性粒细胞浸润和真皮血管改变为特征的皮肤病的综述揭示了证据,表明这些皮肤病是由免疫复合物介导、嗜中性粒细胞诱导的真皮血管损伤所致。针对这些此前未关联的皮肤病的治疗方法非常相似。

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