Brenner C, Nakayama N, Goebl M, Tanaka K, Toh-e A, Matsumoto K
Department of Molecular Biology, DNAX Research Institute of Molecular and Cellular Biology, Palo Alto, California 94304.
Mol Cell Biol. 1988 Aug;8(8):3556-9. doi: 10.1128/mcb.8.8.3556-3559.1988.
The bcy1 mutation makes the cdc33 start mutant arrest at random points in the cell cycle instead of only at G1. We cloned and sequenced CDC33. This coding sequence is identical to that of the gene encoding the Saccharomyces cerevisiae 24-kilodalton mRNA cap-binding protein, eIF-4E.
bcy1突变使cdc33起始突变体在细胞周期的随机点停滞,而不是仅在G1期停滞。我们克隆并测序了CDC33。该编码序列与编码酿酒酵母24千道尔顿mRNA帽结合蛋白eIF-4E的基因序列相同。