Asadi Zahra, Shafiee Mojtaba, Sadabadi Fatemeh, Saberi-Karimian Maryam, Darroudi Susan, Tayefi Maryam, Ghazizadeh Hamideh, Heidari Bakavoli Alireza, Moohebati Mohsen, Esmaeily Habibollah, Ferns Gordon A, Ghayour-Mobarhan Majid
Department of Nutrition, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran; Student Research Committee, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Department of Nutrition, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Diabetes Metab Syndr. 2019 Jan-Feb;13(1):858-865. doi: 10.1016/j.dsx.2018.11.059. Epub 2018 Dec 1.
The role of dietary patterns in metabolic syndrome has not been investigated sufficiently among Iranian population. The aim of this study is to investigate the association of major dietary patterns with the risk of metabolic syndrome and its components among healthy individuals of Iran.
This is a cross-sectional study that was performed on 5895 men and women who participated in MASHAD study project. Factor analysis was employed to determine major dietary patterns with regard to a validated 65-item food frequency questionnaire. Metabolic syndrome was diagnosed using international diabetes federation (IDF). Logistic regression analysis was used to evaluate the association between dietary patterns and metabolic syndrome risk to generate odds ratios (ORs) and 95% confidence intervals (CI).
Three major dietary patterns (Balanced, Western and high carbohydrate) were identified. The Western pattern showed a positive association with metabolic syndrome (OR [95%CI] for highest vs. lowest tertile: 1.58 [1.21-2.06]; p value = 0.001). The high carbohydrate dietary pattern was associated with higher metabolic syndrome risk (OR [95%CI] for highest vs. lowest tertile: 1.17 [1.02-1.33]; P value = 0.022). The Balanced dietary pattern was unrelated to metabolic syndrome, but was related to some individual risk factors for metabolic syndrome.
These results suggest that the Western and high carbohydrate patterns are associated with an increased risk for metabolic syndrome among Iranian adults. The causality of these associations needs to be confirmed.
在伊朗人群中，饮食模式在代谢综合征中的作用尚未得到充分研究。本研究旨在调查伊朗健康个体中主要饮食模式与代谢综合征及其各组分风险之间的关联。
这是一项横断面研究，对参与马什哈德研究项目的5895名男性和女性进行。采用因子分析，根据一份经过验证的包含65个条目的食物频率问卷确定主要饮食模式。使用国际糖尿病联盟（IDF）的标准诊断代谢综合征。采用逻辑回归分析评估饮食模式与代谢综合征风险之间的关联，以生成比值比（OR）和95%置信区间（CI）。
确定了三种主要饮食模式（均衡型、西方型和高碳水化合物型）。西方型饮食模式与代谢综合征呈正相关（最高三分位数与最低三分位数相比的OR[95%CI]：1.58[1.21 - 2.06]；P值 = 0.001）。高碳水化合物饮食模式与更高的代谢综合征风险相关（最高三分位数与最低三分位数相比的OR[95%CI]：1.17[1.02 - 1.33]；P值 = 0.022）。均衡型饮食模式与代谢综合征无关，但与一些代谢综合征的个体风险因素有关。
这些结果表明，西方型和高碳水化合物型饮食模式与伊朗成年人代谢综合征风险增加有关。这些关联的因果关系需要进一步证实。
