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本文引用的文献

1
Polyunsaturated fatty acids for the primary and secondary prevention of cardiovascular disease.用于心血管疾病一级和二级预防的多不饱和脂肪酸
Cochrane Database Syst Rev. 2018 Jul 18;7(7):CD012345. doi: 10.1002/14651858.CD012345.pub2.
2
Fluctuations in blood biomarkers of head trauma in NCAA football athletes over the course of a season.美国大学体育协会(NCAA)橄榄球运动员在一个赛季中头部创伤血液生物标志物的波动情况。
J Neurosurg. 2018 May 29;130(5):1655-1662. doi: 10.3171/2017.12.JNS172035. Print 2019 May 1.
3
American-Style Football and Cardiovascular Health.美式橄榄球与心血管健康。
J Am Heart Assoc. 2018 Apr 4;7(8):e008620. doi: 10.1161/JAHA.118.008620.
4
Protection Before Impact: the Potential Neuroprotective Role of Nutritional Supplementation in Sports-Related Head Trauma.撞击前的保护:营养补充在运动相关性颅脑损伤中的潜在神经保护作用。
Sports Med. 2018 Mar;48(Suppl 1):39-52. doi: 10.1007/s40279-017-0847-3.
5
The Omega-3 Index and relative risk for coronary heart disease mortality: Estimation from 10 cohort studies.ω-3指数与冠心病死亡率的相对风险:来自10项队列研究的估计
Atherosclerosis. 2017 Jul;262:51-54. doi: 10.1016/j.atherosclerosis.2017.05.007. Epub 2017 May 6.
6
Red blood cell PUFAs reflect the phospholipid PUFA composition of major organs.红细胞多不饱和脂肪酸反映了主要器官的磷脂多不饱和脂肪酸组成。
Prostaglandins Leukot Essent Fatty Acids. 2016 Sep;112:12-23. doi: 10.1016/j.plefa.2016.06.004. Epub 2016 Aug 8.
7
Global survey of the omega-3 fatty acids, docosahexaenoic acid and eicosapentaenoic acid in the blood stream of healthy adults.全球范围内健康成年人血液中ω-3 脂肪酸、二十二碳六烯酸和二十碳五烯酸的调查。
Prog Lipid Res. 2016 Jul;63:132-52. doi: 10.1016/j.plipres.2016.05.001. Epub 2016 May 20.
8
Cumulative Head Impact Exposure Predicts Later-Life Depression, Apathy, Executive Dysfunction, and Cognitive Impairment in Former High School and College Football Players.累积头部撞击暴露可预测前高中和大学橄榄球运动员晚年的抑郁、冷漠、执行功能障碍和认知障碍。
J Neurotrauma. 2017 Jan 15;34(2):328-340. doi: 10.1089/neu.2016.4413. Epub 2016 Jun 15.
9
Effect of Docosahexaenoic Acid on a Biomarker of Head Trauma in American Football.二十二碳六烯酸对美式橄榄球头部创伤生物标志物的影响。
Med Sci Sports Exerc. 2016 Jun;48(6):974-82. doi: 10.1249/MSS.0000000000000875.
10
Serum Neurofilament Light in American Football Athletes over the Course of a Season.美式足球运动员一个赛季期间的血清神经丝轻链水平
J Neurotrauma. 2016 Oct 1;33(19):1784-1789. doi: 10.1089/neu.2015.4295. Epub 2016 Mar 16.

国家大学体育协会一级大学橄榄球运动员的欧米伽-3 指数。

The Omega-3 Index in National Collegiate Athletic Association Division I Collegiate Football Athletes.

机构信息

The Sport Science Center at Texas Christian University, Fort Worth.

Department of Dietetics and Nutrition, University of Kansas Medical Center, Kansas City.

出版信息

J Athl Train. 2019 Jan;54(1):7-11. doi: 10.4085/1062-6050-387-18. Epub 2019 Jan 15.

DOI:10.4085/1062-6050-387-18
PMID:30645147
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6410989/
Abstract

CONTEXT

The essential omega-3 fatty acids (ω-3 FAs) eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) exhibit vital biological roles and are critical for cardiovascular and neurologic health. Compared with the general population, football athletes may be at an increased risk of cardiovascular disease. Further, those same athletes are also exposed to repetitive head impacts, which may lead to long-term neurologic deficits. Both diets high in ω-3 FAs and supplementation with ω-3 FAs have been reported to reduce the risk of cardiovascular disease, and early evidence suggests a potential neuroprotective effect of supplementation.

OBJECTIVE

To determine the (1) erythrocyte content of DHA and EPA, as measured by the Omega-3 Index, expressed as a percentage of total fatty acids, in National Collegiate Athletic Association Division I football athletes and (2) distribution across the Omega-3 Index risk zones established for cardiovascular disease: high risk, <4%; intermediate risk, 4% to 8%; and low risk, >8%.

DESIGN

Cross-sectional descriptive study.

SETTING

Multicenter trial.

PATIENTS OR OTHER PARTICIPANTS

Deidentified data including complete erythrocyte fatty acid profile from the 2017-2018 season, age at time of testing, height, weight, and ethnicity were collected from 404 athletes.

MAIN OUTCOME MEASURE(S): Omega-3 Index.

RESULTS

About 34% of athletes (n = 138) had an Omega-3 Index considered high risk (<4%), and 66% (n = 266) had a risk considered intermediate (4%-8%). None had a low-risk Omega-3 Index.

CONCLUSIONS

The Omega-3 Index is a simple, minimally invasive test of ω-3 FA status. Our data indicate that football athletes may be deficient in the ω-3 FAs DHA and EPA. The fact that no athlete had an Omega-3 Index associated with low risk suggests football athletes may be at increased risk for cardiovascular disease in later life.

摘要

背景

必需的ω-3 脂肪酸(ω-3 FAs)二十碳五烯酸(EPA)和二十二碳六烯酸(DHA)具有重要的生物学作用,对心血管和神经系统健康至关重要。与一般人群相比,足球运动员患心血管疾病的风险可能增加。此外,同样的运动员还会受到反复的头部冲击,这可能导致长期的神经缺陷。高 ω-3 FA 饮食和 ω-3 FA 补充都被报道可以降低心血管疾病的风险,早期证据表明补充 ω-3 FA 具有潜在的神经保护作用。

目的

确定(1)国家大学体育协会(NCAA)一级足球运动员红细胞中 DHA 和 EPA 的含量,用 ω-3 指数表示,以总脂肪酸的百分比表示,以及(2)在心血管疾病建立的 ω-3 指数风险区的分布:高风险,<4%;中风险,4%-8%;低风险,>8%。

设计

横断面描述性研究。

地点

多中心试验。

患者或其他参与者

从 2017-2018 赛季收集了 404 名运动员的匿名数据,包括完整的红细胞脂肪酸谱、测试时的年龄、身高、体重和种族,以及完整的红细胞脂肪酸谱、测试时的年龄、身高、体重和种族。

主要观察指标

ω-3 指数。

结果

约 34%的运动员(n = 138)的 ω-3 指数被认为是高风险(<4%),66%(n = 266)的风险被认为是中风险(4%-8%)。没有人的 ω-3 指数处于低风险。

结论

ω-3 指数是一种简单、微创的 ω-3 FA 状态测试。我们的数据表明,足球运动员可能缺乏 DHA 和 EPA 等 ω-3 FAs。没有运动员的 ω-3 指数与低风险相关,这表明足球运动员在以后的生活中可能患心血管疾病的风险增加。