CENRM and School of Population and Global Health, University of Western Australia, Perth, Australia.
Department of Pathobiology and Medical Diagnostics, Faculty of Medicine and Health Sciences, Universiti Malaysia Sabah, Kota Kinabalu, Malaysia.
Ecohealth. 2019 Dec;16(4):594-610. doi: 10.1007/s10393-019-01395-6. Epub 2019 Jan 23.
Defining the linkages between landscape change, disease ecology and human health is essential to explain and predict the emergence of Plasmodium knowlesi malaria, a zoonotic parasite residing in Southeast Asian macaques, and transmitted by species of Anopheles mosquitos. Changing patterns of land use throughout Southeast Asia, particularly deforestation, are suggested to be the primary drivers behind the recent spread of this zoonotic parasite in humans. Local ecological changes at the landscape scale appear to be increasing the risk of disease in humans by altering the dynamics of transmission between the parasite and its primary hosts. This paper will focus on the emergence of P. knowlesi in humans in Malaysian Borneo and the ecological linkage mechanisms suggested to be playing an important role.
定义景观变化、疾病生态学和人类健康之间的联系对于解释和预测疟原虫 knowlesi 疟疾的出现至关重要，疟原虫 knowlesi 是一种寄生于东南亚猕猴身上的动物源性寄生虫，由疟蚊属的蚊子传播。东南亚各地土地利用方式的变化，特别是森林砍伐，被认为是这种动物源性寄生虫在人类中最近传播的主要驱动因素。景观尺度上的局部生态变化似乎通过改变寄生虫与其主要宿主之间的传播动态，增加了人类患病的风险。本文将重点关注马来西亚婆罗洲人类疟原虫 knowlesi 的出现，以及被认为发挥重要作用的生态联系机制。
