Department of Paediatrics, University of Melbourne, Melbourne, Victoria, Australia.
Murdoch Children's Research Institute, Melbourne, Victoria, Australia.
J Med Ethics. 2019 Aug;45(8):514-523. doi: 10.1136/medethics-2018-105084. Epub 2019 Jan 24.
In July 2018, the Nuffield Council of Bioethics released its long-awaited report on heritable genome editing (HGE). The Nuffield report was notable for finding that HGE could be morally permissible, even in cases of human enhancement. In this paper, we summarise the findings of the Nuffield Council report, critically examine the guiding principles they endorse and suggest ways in which the guiding principles could be strengthened. While we support the approach taken by the Nuffield Council, we argue that detailed consideration of the moral implications of genome editing yields much stronger conclusions than they draw. Rather than being merely 'morally permissible', many instances of genome editing will be moral imperatives.
2018 年 7 月，英国纳菲尔德生物伦理学理事会发布了其期待已久的关于可遗传基因组编辑的报告。该报告值得注意的是，它发现可遗传基因组编辑在人类增强的情况下也可能在道德上是允许的。在本文中，我们总结了英国纳菲尔德理事会报告的调查结果，批判性地审查了他们认可的指导原则，并提出了加强这些指导原则的方法。虽然我们支持英国纳菲尔德理事会采取的方法，但我们认为，对基因组编辑的道德影响进行详细考虑会得出比他们更有力的结论。许多情况下的基因组编辑将不仅仅是“在道德上是允许的”，而是道德上的必然要求。
