Cohn-Sheehy Brendan I, Ranganath Charan
Center for Neuroscience, University of California, Davis, CA, 95618, USA.
Neuroscience Graduate Group, University of California, Davis, CA, 95618, USA.
Curr Opin Behav Sci. 2017 Oct;17:169-177. doi: 10.1016/j.cobeha.2017.08.005. Epub 2017 Sep 13.
Life's episodes unfold against a context that changes with time. Recent neuroimaging studies have revealed significant findings about how specific areas of the human brain may support the representation of temporal information in memory. A consistent theme in these studies is that the hippocampus appears to play a central role in representing temporal context, as operationalized in neuroimaging studies of arbitrary lists of items, sequences of items, or meaningful, lifelike events. Additionally, activity in a posterior medial cortical network may reflect the representation of generalized temporal information for meaningful events. The hippocampus, posterior medial network, and other regions-particularly in prefrontal cortex-appear to play complementary roles in memory for temporal context.
人生的各个阶段是在一个随时间变化的背景中展开的。最近的神经影像学研究揭示了关于人类大脑特定区域如何支持记忆中时间信息表征的重要发现。这些研究中的一个一致主题是,在对任意项目列表、项目序列或有意义的、逼真的事件进行神经影像学研究时,海马体似乎在表征时间背景方面发挥着核心作用。此外,后内侧皮质网络中的活动可能反映了有意义事件的广义时间信息的表征。海马体、后内侧网络和其他区域——特别是前额叶皮质中的区域——似乎在时间背景记忆中发挥着互补作用。