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基于散斑分析的远程光声传感。

Remote photoacoustic sensing using speckle-analysis.

机构信息

Institute of Photonic Technologies (LPT), Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), Konrad-Zuse-Straße 3/5, 91052, Erlangen, Germany.

Erlangen Graduate School in Advanced Optical Technologies (SAOT), Paul-Gordan-Straße 6, 91052, Erlangen, Germany.

出版信息

Sci Rep. 2019 Jan 31;9(1):1057. doi: 10.1038/s41598-018-38446-x.

Abstract

Laser surgery is a rising surgical technique, which offers several advantages compared to the traditional scalpel. However, laser surgery lacks a contact-free feedback system which offers high imaging contrast to identify the tissue type ablated and also a high penetration depth. Photoacoustic imaging has the potential to fill this gap. Since photoacoustic detection is commonly contact based, a new non-interferometric detection technique based on speckle-analysis for remote detection is presented in this work. Phantom and ex-vivo experiments are carried out in transmission and reflection-mode for proof of concept. In summary, the potential of the remote speckle sensing technique for photoacoustic detection is demonstrated. In future, this technique might be applied for usage as a remote feedback system for laser surgery, which could help to broaden the applications of lasers as smart surgical tools.

摘要

激光手术是一种新兴的手术技术,与传统手术刀相比具有多项优势。然而,激光手术缺乏一种非接触式反馈系统,该系统提供高对比度的成像来识别被烧蚀的组织类型,并且具有高穿透深度。光声成像是一种有潜力的方法。由于光声检测通常是基于接触的,因此在这项工作中提出了一种新的基于散斑分析的非干涉检测技术,用于远程检测。在传输和反射模式下进行了体模和离体实验,以验证其概念。总之,远程散斑传感技术用于光声检测的潜力得到了证明。将来,这项技术可能会被应用于激光手术的远程反馈系统,这有助于拓宽激光作为智能手术工具的应用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cee5/6355860/0450c239ab7f/41598_2018_38446_Fig1_HTML.jpg

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