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Transcriptome analysis reveals the role of the PCP pathway in fipronil and endotoxin-induced lung damage.

作者信息

Pandit Arif Ahmad, Gandham Ravi Kumar, Mukhopadhyay C S, Verma Ramneek, Sethi R S

机构信息

Department of Animal Biotechnology, School of Animal Biotechnology, Guru Angad Dev Veterinary and Animals Sciences University, Ludhiana, Punjab, 141004, India.

Division of Veterinary Biotechnology, ICAR-Indian Veterinary Research Institute [Deemed University], Izatnagar, Bareilly, UP, India. National Institute of Animal Biotechnology, Hyderabad, India.

出版信息

Respir Res. 2019 Feb 1;20(1):24. doi: 10.1186/s12931-019-0986-1.

DOI:10.1186/s12931-019-0986-1
PMID:30709343
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6359862/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/655a/6359862/290f2a76865b/12931_2019_986_Fig9_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/655a/6359862/a912740d28ad/12931_2019_986_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/655a/6359862/8ef0b43ca06d/12931_2019_986_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/655a/6359862/dc158fccbbcc/12931_2019_986_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/655a/6359862/c15d0bf0379a/12931_2019_986_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/655a/6359862/70d2706b20e6/12931_2019_986_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/655a/6359862/5bada677572e/12931_2019_986_Fig6_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/655a/6359862/c3e3e43a81eb/12931_2019_986_Fig7_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/655a/6359862/02b881d3db7d/12931_2019_986_Fig8_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/655a/6359862/290f2a76865b/12931_2019_986_Fig9_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/655a/6359862/a912740d28ad/12931_2019_986_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/655a/6359862/8ef0b43ca06d/12931_2019_986_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/655a/6359862/dc158fccbbcc/12931_2019_986_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/655a/6359862/c15d0bf0379a/12931_2019_986_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/655a/6359862/70d2706b20e6/12931_2019_986_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/655a/6359862/5bada677572e/12931_2019_986_Fig6_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/655a/6359862/c3e3e43a81eb/12931_2019_986_Fig7_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/655a/6359862/02b881d3db7d/12931_2019_986_Fig8_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/655a/6359862/290f2a76865b/12931_2019_986_Fig9_HTML.jpg

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Long-term exposures to ethion and endotoxin cause lung inflammation and induce genotoxicity in mice.长期暴露于乙硫磷和内毒素会导致小鼠肺部炎症，并诱发遗传毒性。
Cell Tissue Res. 2019 Feb;375(2):493-505. doi: 10.1007/s00441-018-2912-0. Epub 2018 Sep 17.
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