Tang Junqi, Ou Quanhong, Zhou Haichun, Qi Limin, Man Shiqing
Yunnan Key laboratory of Optoelectronic Information Technology, College of Physics and Electronic Information, Yunnan Normal University, Kunming 650500, Yunnan, China.
Beijing National Laboratory for Molecular Sciences, College of Chemistry, Peking University, Beijing 100871, China.
Nanomaterials (Basel). 2019 Feb 1;9(2):185. doi: 10.3390/nano9020185.
A seed-mediated electroless deposition (SMED) approach for fabrication of large-area and uniform gold nanoparticle films as efficient and reproducible as surface-enhanced Raman scattering (SERS) substrates was presented. This approach involved a seeding pretreatment procedure and a subsequent growth step. The former referred to activation of polylysine-coated glass slides in gold seed solution, and the latter required a careful control of the reactant concentration and reaction time. With the aid of gold seeds and appropriate reaction conditions, a large-area and uniform nanofilm with evenly distributed gold nanoparticles (Au NPs) was formed on the surface of the substrates after adding a mixed solution containing ascorbic acid and trisodium citrate. The morphology of the Au nanofilm was examined by scanning electron microscopy. The size evolution of Au NPs on the surface of the substrates was analyzed in detail. The nanofilm substrate was prepared by reaction conditions of the seeded activation process: 10 mL ascorbic acid and trisodium citrate mixture and 30 min of soaking time, which exhibited an excellent uniformity and reproducibility of SERS enhancement with relative standard deviation (RSD) values of less than 8% (particularly, a RSD value of 3% can be reached for the optimized measurement). Compared to the common electroless deposition, the seed-mediated electroless deposition possessed inherent advantages in controllability, reproducibility, and economic benefit.
提出了一种种子介导的化学沉积（SMED）方法，用于制备大面积且均匀的金纳米颗粒薄膜，该薄膜作为表面增强拉曼散射（SERS）基底具有高效性和可重复性。这种方法包括种子预处理步骤和随后的生长步骤。前者是指在金种子溶液中对聚赖氨酸包被的载玻片进行活化，后者则需要仔细控制反应物浓度和反应时间。借助金种子和合适的反应条件，在加入含有抗坏血酸和柠檬酸三钠的混合溶液后，在基底表面形成了具有均匀分布的金纳米颗粒（Au NPs）的大面积且均匀的纳米薄膜。通过扫描电子显微镜检查了金纳米薄膜的形态。详细分析了基底表面金纳米颗粒的尺寸演变。通过种子活化过程的反应条件制备纳米薄膜基底：10 mL抗坏血酸和柠檬酸三钠混合物以及30分钟的浸泡时间，其表现出优异的SERS增强均匀性和可重复性，相对标准偏差（RSD）值小于8%（特别是，优化测量时可达到3%的RSD值）。与普通化学沉积相比，种子介导的化学沉积在可控性、可重复性和经济效益方面具有固有优势。
