Alidjanov Jakhongir F, Naber Kurt G, Abdufattaev Ulugbek A, Pilatz Adrian, Wagenlehner Florian M E
The Republican Specialized Center of Urology, 100109 Tashkent, Uzbekistan.
Clinic of Urology, Paediatric Urology and Andrology, Justus-Liebig-University, 35392 Giessen, Germany.
Antibiotics (Basel). 2018 Jan 15;7(1):6. doi: 10.3390/antibiotics7010006.
This study aimed to reevaluate the Acute Cystitis Symptom Score (ACSS). The ACSS is a simple and standardized self-reporting questionnaire for the diagnosis of acute uncomplicated cystitis (AC) assessing typical and differential symptoms, quality of life, and possible changes after therapy in female patients with AC. This paper includes literature research, development and evaluation of the ACSS, an 18-item self-reporting questionnaire including (a) six questions about "typical" symptoms of AC, (b) four questions regarding differential diagnoses, (c) three questions on quality of life, and (d) five questions on additional conditions that may affect therapy. The ACSS was evaluated in 228 women (mean age 31.49 ± 11.71 years) in the Russian and Uzbek languages. Measurements of reliability, validity, predictive ability, and responsiveness were performed. Cronbach's alpha for ACSS was 0.89, split-half reliability was 0.76 and 0.79 for first and second halves, and the correlation between them was 0.87. Mann-Whitney U test revealed a significant difference in scores of the "typical" symptoms between patients and controls (10.50 vs. 2.07, p < 0.001). The optimal threshold score was 6 points, with a 94% sensitivity and 90% specificity to predict AC. The "typical" symptom score decreased significantly when comparing before and after therapy (10.4 and 2.5, p < 0.001). The reevaluated Russian and Uzbek ACSS are accurate enough and can be recommended for clinical studies and practice for initial diagnosis and monitoring the process of the treatment of AC in women. Evaluation in German, UK English, and Hungarian languages was also performed and in other languages evaluation of the ACSS is in progress.
本研究旨在重新评估急性膀胱炎症状评分（ACSS）。ACSS是一种简单且标准化的自我报告问卷，用于诊断急性单纯性膀胱炎（AC），评估女性AC患者的典型症状和鉴别症状、生活质量以及治疗后的可能变化。本文包括ACSS的文献研究、开发与评估，这是一份包含18个项目的自我报告问卷，包括（a）六个关于AC“典型”症状的问题，（b）四个关于鉴别诊断的问题，（c）三个关于生活质量的问题，以及（d）五个关于可能影响治疗的附加情况的问题。ACSS在228名女性（平均年龄31.49±11.71岁）中用俄语和乌兹别克语进行了评估。进行了可靠性、有效性、预测能力和反应性的测量。ACSS的Cronbach's alpha系数为0.89，分半信度在问卷前半部分和后半部分分别为0.76和0.79，两者之间的相关性为0.87。曼-惠特尼U检验显示患者与对照组在“典型”症状评分上存在显著差异（10.50对2.07，p<0.001）。预测AC的最佳阈值分数为6分，敏感性为94%，特异性为90%时。治疗前后比较，“典型”症状评分显著降低（10.4和2.5，p<0.001）。重新评估后的俄语和乌兹别克语ACSS足够准确，可推荐用于临床研究和实践，以对女性AC进行初步诊断和监测治疗过程。还对德语、英国英语和匈牙利语进行了评估，对ACSS在其他语言中的评估正在进行中。
