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3D Printed Stem-Cell Derived Neural Progenitors Generate Spinal Cord Scaffolds.3D打印的干细胞衍生神经祖细胞生成脊髓支架。
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2
Biomimetic 3D-printed scaffolds for spinal cord injury repair.仿生 3D 打印支架治疗脊髓损伤。
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Personalized Hydrogels for Engineering Diverse Fully Autologous Tissue Implants.个性化水凝胶用于工程化多样化的全自体组织植入物。
Adv Mater. 2019 Jan;31(1):e1803895. doi: 10.1002/adma.201803895. Epub 2018 Nov 8.
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Commercial Scale Manufacturing of Allogeneic Cell Therapy.异基因细胞疗法的商业化规模生产。
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Advances in Regenerative Medicine and Tissue Engineering: Innovation and Transformation of Medicine.再生医学与组织工程学进展:医学的创新与变革
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6
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追逐范式:组织工程 25 年的临床转化。

Chasing the Paradigm: Clinical Translation of 25 Years of Tissue Engineering.

机构信息

1 Department of Bioengineering, University of California, Los Angeles, California.

2 Center for Minimally Invasive Therapeutics (C-MIT), University of California, Los Angeles, California.

出版信息

Tissue Eng Part A. 2019 May;25(9-10):679-687. doi: 10.1089/ten.TEA.2019.0032.

DOI:10.1089/ten.TEA.2019.0032
PMID:30727841
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6533781/
Abstract

In this Perspective, we discuss the impact of the past 25 years of tissue engineering on the development of clinical therapies. Based on their success and other significant research accomplishments, platforms of innovation were identified. Their discoveries will enable tissue engineering inspired therapies to meet the requirements necessary for large-scale manufacturing and Food and Drug Administration (FDA) approval for a diverse range of indications.

摘要

在本观点中,我们讨论了过去 25 年组织工程对临床治疗发展的影响。基于它们的成功和其他重要的研究成果,确定了创新平台。它们的发现将使组织工程灵感的治疗方法能够满足大规模制造和美国食品和药物管理局(FDA)批准各种适应症的要求。