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影响全科医生采用新处方药决策的因素——利用澳大利亚纵向医生调查数据进行队列分析

Factors affecting general practitioners' decisions to adopt new prescription drugs - cohort analyses using Australian longitudinal physician survey data.

作者信息

Zhang Yuting, Méndez Susan J, Scott Anthony

机构信息

Melbourne Institute: Applied Economic and Social Research, Faculty of Business and Economics, The University of Melbourne, 5th floor, FBE Building 111 Barry St, Carlton, VIC, 3010, Australia.

出版信息

BMC Health Serv Res. 2019 Feb 7;19(1):94. doi: 10.1186/s12913-019-3889-4.

Abstract

BACKGROUND

We investigate factors affecting Australian general practitioners' decisions to adopt novel oral anticoagulants (NOACs) for the prevention of stroke/systemic embolism among patients with atrial fibrillation. Australia has a national homogeneous review and coverage system, which enables us to distinguish physician level factors while maintaining system level factors and patient coverage information constant.

METHODS

We conduct a cohort analyses by using longitudinal physician survey data from the Medicine in Australia: Balancing Employment and Life panel survey of Australian physicians (MABEL). MABEL data contain rich physician-level information such as age, gender, education, risk preferences, personality, physicians' communications with other medical professionals, and other practice characteristics. Importantly, the survey data were linked, with physician's consent, to actual utilization data from the Australian Pharmaceutical Benefits Scheme and the Medicare Benefits Schedule between January 1, 2012 and December 31, 2015. We measure speed (days until first time prescribing) of adopting NOACs. We estimate a Cox proportional hazard model to estimate factors affecting the adoption speed.

RESULTS

Several factors predict earlier adoption of NOACs: being male, more likely to take clinical risk, higher prescribing volume, being a principal or partner in the practice instead of an employee, spending less time in a typical consultation, and practicing in more affluent areas or areas with a higher proportion of older patients. GPs in Queensland are more likely to adopt NOACs and more likely to be extensive early adopters compared to other GPs. Other characteristics including physician personality, family circumstances, their involvement with public hospitals and teaching activities, and the distance between physician practice location to other clinics in the area are not statistically associated with earlier adoption.

CONCLUSIONS

Our paper is one of the first to study the relationship between GPs' risk preferences, personality and their decisions to adopt new prescription drugs. Because NOACs are commonly prescribed and considered more cost-effective than their older counterpart, understanding factors affecting physicians' decisions to adopt NOACs has direct policy implications. Our results also highlight that even with universal coverage for prescription drugs, access to new drugs is different among patients, partially because who their doctors are and where they practice.

摘要

背景

我们调查了影响澳大利亚全科医生采用新型口服抗凝药(NOACs)预防房颤患者中风/全身性栓塞决策的因素。澳大利亚有一个全国统一的评审和覆盖体系,这使我们能够在保持系统层面因素和患者覆盖信息不变的情况下,区分医生层面的因素。

方法

我们使用来自澳大利亚医生就业与生活平衡小组调查(MABEL)的纵向医生调查数据进行队列分析。MABEL数据包含丰富的医生层面信息,如年龄、性别、教育程度、风险偏好、性格、医生与其他医疗专业人员的沟通以及其他执业特征。重要的是,经医生同意,调查数据与2012年1月1日至2015年12月31日期间澳大利亚药品福利计划和医疗保险福利计划的实际使用数据相关联。我们衡量采用NOACs的速度(首次开处方前的天数)。我们估计一个Cox比例风险模型来估计影响采用速度的因素。

结果

几个因素预示着更早采用NOACs:男性、更倾向于承担临床风险、更高的处方量、是诊所的负责人或合伙人而非雇员、在典型会诊中花费时间较少,以及在更富裕地区或老年患者比例较高的地区执业。与其他全科医生相比,昆士兰的全科医生更有可能采用NOACs,且更有可能成为广泛的早期采用者。其他特征,包括医生性格、家庭情况、他们参与公立医院和教学活动的情况,以及医生执业地点与该地区其他诊所之间的距离,与更早采用没有统计学关联。

结论

我们的论文是首批研究全科医生风险偏好、性格与他们采用新处方药决策之间关系的论文之一。由于NOACs被普遍处方且被认为比其旧药更具成本效益,了解影响医生采用NOACs决策的因素具有直接的政策意义。我们的结果还强调,即使处方药实现了全民覆盖,患者获得新药的机会也存在差异,部分原因在于他们的医生是谁以及在哪里执业。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3d61/6366109/4ee6d89c87fc/12913_2019_3889_Fig1_HTML.jpg

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