Department of Biotechnology, Manipal Institute of Technology, Manipal Academy of Higher Education, Manipal, 576104, Karnataka, India.
Department of Mechanical Engineering, Indian Institute of Technology Kharagpur, Kharagpur, 721302, India.
Sci Rep. 2019 Feb 11;9(1):1752. doi: 10.1038/s41598-018-38308-6.
We present a rapid (<10 s), cost-effective, unique single-step method for fabricating paper-based devices without necessitating any expensive instrumentation, simply by deploying correction pens that are otherwise commonly used for masking typos in printed or written matters. The marked regions formed by deposits from the correction pen demonstrate ubiquitous flow resistances to typical aqueous solutions and organic solvents in the transverse direction, resulting in a preferential bulk flow along the axial direction of the paper channels 'fabricated' in the process. Considering the simplicity and cost-effectiveness of this platform, it is deemed to be ideal for (bio) chemical sensing and point-of-care diagnostics in resource-limited settings.
我们提出了一种快速（<10 秒）、经济高效、独特的单步制造基于纸张的器件的方法，而无需任何昂贵的仪器，只需使用通常用于掩盖印刷品或手写品中错别字的修正笔即可。修正笔留下的标记区域在横向方向上对典型的水溶液和有机溶剂表现出普遍的流动阻力，从而导致在该过程中“制造”的纸通道的轴向方向上优先进行体流。考虑到该平台的简单性和成本效益，它被认为非常适合资源有限环境中的（生物）化学传感和即时诊断。
