Gstraunthaler G J
Institute of Physiology, University of Innsbruck, Austria.
Ren Physiol Biochem. 1988 Jan-Feb;11(1-2):1-42. doi: 10.1159/000173147.
In this review the characteristics of established renal and intestinal epithelial cell lines are described by summarizing the accumulated literature about specific properties retained by the cells in tissue culture. Furthermore, brief examples are given for the use of cultured epithelia as model systems to study epithelial transport and metabolic functions, epithelial cell polarity, and aspects of the differentiation and maturation of epithelia by physiological, biochemical and genetic, or cell and molecular biological approaches.
在本综述中，通过总结组织培养中细胞所保留的特定特性的累积文献，描述了已建立的肾和肠上皮细胞系的特征。此外，还给出了简短的例子，说明如何将培养的上皮细胞用作模型系统，通过生理学、生物化学和遗传学或细胞与分子生物学方法来研究上皮运输和代谢功能、上皮细胞极性以及上皮细胞分化和成熟的各个方面。
