Beilin L J
University Department of Medicine, Royal Perth Hospital, Australia.
Drugs. 1988;36 Suppl 6:1-9. doi: 10.2165/00003495-198800366-00003.
The benefits of the treatment of hypertension currently consist of a substantially reduced incidence of premature stroke, left ventricular failure and malignant hypertension. The benefits for the individual are most clearcut in those who have already had severe or symptomatic hypertension. Older subjects who have a higher risk of stroke and heart failure also show more immediate benefits in terms of stroke and heart failure reduction. However, in the community as a whole, mild hypertensives account for over half the cardiovascular deaths attributable to high blood pressure. In such patients a more systematic approach to the use of non-pharmacological measures for both control of blood pressure and coronary heart disease, coupled where necessary with the judicious use of existing and new antihypertensive and lipid lowering drugs, offers the prospect for a new era of prevention in relation to hypertensive cardiovascular disease.
目前,高血压治疗的益处包括显著降低早发性中风、左心室衰竭和恶性高血压的发病率。对于那些已经患有严重高血压或症状性高血压的个体而言,治疗的益处最为明显。中风和心力衰竭风险较高的老年受试者在降低中风和心力衰竭方面也显示出更直接的益处。然而,在整个社区中,轻度高血压患者占因高血压导致的心血管死亡人数的一半以上。对于这类患者,采用更系统的方法使用非药物措施来控制血压和冠心病,必要时合理使用现有的和新的抗高血压及降脂药物,有望开创高血压心血管疾病预防的新时代。