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EXCLI J. 2014 Nov 4;13:1204-15. eCollection 2014.
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Level set method for segmentation of infrared breast thermograms.用于红外乳腺热成像图分割的水平集方法
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Wavelet-based 3D reconstruction of microcalcification clusters from two mammographic views: new evidence that fractal tumors are malignant and Euclidean tumors are benign.基于小波的从两个乳腺X线视图对微钙化簇进行三维重建:分形肿瘤为恶性而欧几里得肿瘤为良性的新证据。
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Fractal-like kinetics, a possible link between preconditioning and sepsis immunodepression. On the chemical basis of innate immunity.类分形动力学,预处理与脓毒症免疫抑制之间的一种可能联系。基于先天免疫的化学基础。
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Fractal analysis and ionic dependence of endocytotic membrane activity of human breast cancer cells.人乳腺癌细胞内吞膜活性的分形分析及离子依赖性
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Plasmonic photothermal therapy (PPTT) using gold nanoparticles.使用金纳米颗粒的等离激元光热疗法(PPTT)。
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Fractal analysis of mammographic parenchymal patterns in breast cancer risk assessment.乳腺癌风险评估中乳腺钼靶实质模式的分形分析。
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基于乳房热成像分形维数的乳腺癌治疗模糊控制器设计

Fuzzy controller design for breast cancer treatment based on fractal dimension using breast thermograms.

作者信息

Zade Maryam Arab, Khodadadi Hamed

机构信息

Department of Electrical Engineering, Khomeinishahr Branch, Islamic Azad University, Isfahan, Iran.

出版信息

IET Syst Biol. 2019 Feb;13(1):1-7. doi: 10.1049/iet-syb.2018.5020.

DOI:10.1049/iet-syb.2018.5020
PMID:30774110
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8687249/
Abstract

In this study, three non-linear indices consist of compression, one-dimensional (1D) and two-dimensional (2D) fractal dimensions are used for the determination of the malignancy or benignity of cancer tumours in breast thermograms. On the other hand, by developing the high-precision infrared cameras as well as new methods of image processing, biomedical thermography images have found a prominent position among the others. Furthermore, cancerous tissue can be affected by the laser. In this study, in order to treat the cancerous lesion identified by breast thermograms, the laser parameters are designed. The basis of controller designing is the obtained non-linear indices. If the indices are moved from the chaotic behaviour to normal condition, the treating tissue is going from cancerous to a healthy condition and the treatment process is completed. Radiation frequency and the energy density of laser are designed as two key elements in the cancer treatment. In this study, the type I and type II fuzzy controllers are employed for the control strategies. Using the proposed closed-loop control, the non-linear indices of the cancerous lesion will be reduced during the treatment process. The simulation results on two datasets of breast thermograms indicate the superiority of type II fuzzy controller.

摘要

在本研究中,三个非线性指标,即压缩、一维(1D)和二维(2D)分形维,用于确定乳腺热成像图中癌症肿瘤的恶性或良性。另一方面,通过开发高精度红外相机以及新的图像处理方法,生物医学热成像图像在其他图像中占据了突出地位。此外,癌组织会受到激光的影响。在本研究中,为了治疗乳腺热成像图中识别出的癌性病变,设计了激光参数。控制器设计的基础是获得的非线性指标。如果指标从混沌行为转变为正常状态,治疗组织就从癌性状态转变为健康状态,治疗过程即完成。辐射频率和激光能量密度被设计为癌症治疗中的两个关键要素。在本研究中,采用I型和II型模糊控制器作为控制策略。使用所提出的闭环控制,癌性病变的非线性指标在治疗过程中将降低。对两个乳腺热成像图数据集的仿真结果表明了II型模糊控制器的优越性。