Ahmad Ibrahim, Kudi Caleb Ayuba, Abdulkadir Alhaji Idris, Saidu S N A, Chafe Umar Mohammed, Abdulmalik Zainab
Directorate of Animal Health and Livestock Development, Gusau, Zamfara, Nigeria.
Departmet of Veterinary Medicine, Faculty of Veterinary Medicine, Ahmadu Bello University Zaria, Nigeria.
Open Vet J. 2018;8(4):463-470. doi: 10.4314/ovj.v8i4.18. Epub 2018 Dec 12.
Bovine tuberculosis (bTB) is a zoonotic disease caused by complex (MTBC) that primarily affects cattle, but also other domestic and wild mammals. In Nigeria, abattoir monitoring of gross bTB lesions is the only control method being applied in all animals. This study aims to investigate tubercle bacilli infection in slaughtered cattle found with visible tuberculosis-like lesions. Lesions suggesting bTB were detected in 226 cattle during abattoir monitoring in Zamfara State, Nigeria. Tissue samples collected from the affected carcasses were subjected to Ziehl-Neelsen stain (ZN). Of the 226 carcasses with lesions, 37 (16.4%) were positive by the Ziehl-Neelsen stain (ZN), and MTBC was detected from 34 (91.9%) of the 37 ZN-positive samples. Molecular typing by region of difference (RD) deletion analysis revealed the genotype of , and . Infection was most significantly associated with age of the animals (OR = 3.49; CI: 1.29-9.47 [ = 0.002]). The findings indicate a serious threat for health as well as for TB control in Nigeria.
牛结核病（bTB）是一种由结核分枝杆菌复合群（MTBC）引起的人畜共患病，主要影响牛，但也会感染其他家养和野生哺乳动物。在尼日利亚，对所有动物进行屠宰场大体牛结核病变监测是唯一采用的控制方法。本研究旨在调查在屠宰时发现有可见结核样病变的牛的结核杆菌感染情况。在尼日利亚赞法拉州的屠宰场监测期间，在226头牛中检测到提示牛结核的病变。从受影响的 carcasses 采集的组织样本进行了萋-尼氏染色（ZN）。在226头有病变的 carcasses 中，37头（16.4%）经萋-尼氏染色（ZN）呈阳性，在37份ZN阳性样本中的34份（91.9%）检测到MTBC。通过差异区域（RD）缺失分析进行分子分型，揭示了 、 和 的基因型。感染与动物年龄最显著相关（OR = 3.49；CI：（此处原文有误，推测应为1.29 - 9.47）1.29 - 9.47 [ = 0.002]）。这些发现表明对尼日利亚的健康以及结核病控制构成严重威胁。
文中“carcasses”未翻译，因为不清楚其准确含义，根据语境推测可能是“屠体”等意思，可根据实际情况调整。
