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迈向构建植物细胞图谱。

Towards Building a Plant Cell Atlas.

作者信息

Rhee Seung Y, Birnbaum Kenneth D, Ehrhardt David W

机构信息

Carnegie Institution for Science, Department of Plant Biology, Stanford, CA 94305, USA.

New York University, Department of Biology, New York, NY 10003, USA.

出版信息

Trends Plant Sci. 2019 Apr;24(4):303-310. doi: 10.1016/j.tplants.2019.01.006. Epub 2019 Feb 16.

DOI:10.1016/j.tplants.2019.01.006
PMID:30777643
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7449582/
Abstract

Enormous societal challenges, such as feeding and providing energy for a growing population in a dramatically changing climate, necessitate technological advances in plant science. Plant cells are fundamental organizational units that mediate the production, transport, and storage of our primary food sources, and they sequester a significant proportion of the world's carbon. New technologies allow comprehensive descriptions of cells that could accelerate research across fields of plant science. Complementary to the efforts towards understanding the cellular diversity in human brain and immune systems, a Plant Cell Atlas (PCA) that maps molecular machineries to cellular and subcellular domains, follows their dynamic movements, and describes their interactions would accelerate discovery in plant science and help to solve imminent societal problems.

摘要

巨大的社会挑战,如在急剧变化的气候中为不断增长的人口提供食物和能源,需要植物科学的技术进步。植物细胞是介导我们主要食物来源的生产、运输和储存的基本组织单位,并且它们封存了世界上很大一部分碳。新技术能够对细胞进行全面描述,这可能会加速植物科学各个领域的研究。与致力于了解人类大脑和免疫系统中的细胞多样性的努力相辅相成,一个将分子机制映射到细胞和亚细胞区域、追踪其动态运动并描述其相互作用的植物细胞图谱(PCA)将加速植物科学的发现,并有助于解决紧迫的社会问题。

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