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Gm和Km同种异型对链球菌细胞壁抗原细胞免疫反应的交互作用。

Interactive effect of Gm and Km allotypes on cellular immune responses to streptococcal cell wall antigen.

作者信息

Wachsmuth R R, Pandey J P, Fedrick J A, Nishimura Y, Sasazuki T

机构信息

Department of Basic and Clinical Immunology and Microbiology, Medical University of South Carolina, Charleston.

出版信息

Exp Clin Immunogenet. 1987;4(3):163-6.

PMID:3078724
Abstract

Serum samples from 121 unrelated, healthy Japanese individuals were typed for several Gm and Km(1) allotypes. Peripheral blood lymphocytes from these subjects were cultured with streptococcal cell wall (SCW) antigen and the incorporation of 3H-thymidine into T lymphoblasts was measured. Log-linear analysis showed a significant interactive effect of Gm1,17;13,16,21 and Km(1) on the cellular immune response to group A SCW antigen.

摘要

对121名无亲缘关系的健康日本个体的血清样本进行了几种Gm和Km(1)同种异型分型。用链球菌细胞壁(SCW)抗原培养这些受试者的外周血淋巴细胞,并测定3H-胸腺嘧啶核苷掺入T淋巴母细胞的情况。对数线性分析显示,Gm1,17;13,16,21和Km(1)对A组SCW抗原的细胞免疫反应有显著的交互作用。

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