Cooiman M I, Aarts E O, Janssen I M C, Hazebroek E J, Berends F J
Department of Bariatric Surgery, Rijnstate Hospital/Vitalys Clinics, Wagnerlaan, 55, 6815 AD, Arnhem, The Netherlands.
Obes Surg. 2019 Jun;29(6):1851-1857. doi: 10.1007/s11695-019-03781-z.
One of the current criteria for bariatric surgery is to be of an age between 18 and 65 years. In all the available literature, there is a lack of studies focusing on the results of bariatric surgery in younger patient. This could be of great interest because the weight loss response can be altered by differences in metabolism or compliance rate. In recent years, a high amount of patients between 18 and 25 years of age have undergone bariatric surgery in our center, and it is our aim to evaluate the weight loss results in this youngest patient group.
All preoperative and perioperative data from patients aged 18-25 and 35-55 years (control group) were collected retrospectively. Bariatric procedures took place between 2011 and 2014. Follow-up data were gathered prospectively by collecting (laboratory) measurements and questionnaires.
In total, 103 young adults (mean age 22.5) were matched to 103 adult control patients (mean age 42.6) on BMI and date of surgery. Of the young adults' group, 75 patients underwent a Roux-en-Y gastric bypass (RYGB) compared with 80 patients in the control group. Three years after RYGB, mean %total body weight loss (%TBWL) was 34 (± 9) and 30.3 (± 9) (p = 0.03), respectively.
Bariatric surgery is effective in young adults, and results after RYGB are even better compared with age groups in which bariatric surgery is most often performed. The high remission rate of comorbidities shows the importance of effective treatment options at a young age and preventing damaging effects in the long term.
目前减肥手术的标准之一是年龄在18至65岁之间。在所有现有文献中，缺乏针对年轻患者减肥手术结果的研究。这可能会引起极大兴趣，因为体重减轻反应可能会因新陈代谢或依从率的差异而改变。近年来，我们中心有大量18至25岁的患者接受了减肥手术，我们的目的是评估这个最年轻患者群体的体重减轻结果。
回顾性收集了18 - 25岁患者和35 - 55岁患者（对照组）的所有术前和围手术期数据。减肥手术于2011年至2014年进行。通过收集（实验室）测量数据和问卷前瞻性地收集随访数据。
总共103名年轻成年人（平均年龄22.5岁）在BMI和手术日期方面与103名成年对照患者（平均年龄42.6岁）相匹配。在年轻成年人组中，75名患者接受了Roux - en - Y胃旁路术（RYGB），而对照组有80名患者。RYGB术后三年，平均总体重减轻百分比（%TBWL）分别为34（±9）和30.3（±9）（p = 0.03）。
减肥手术对年轻成年人有效，与最常进行减肥手术的年龄组相比，RYGB术后的效果甚至更好。合并症的高缓解率表明了年轻时有效治疗方案的重要性以及长期预防损害性影响的重要性。
