豆类摄入量与非酒精性脂肪性肝病风险
Legume intake and risk of nonalcoholic fatty liver disease.
作者信息
Bahrami Alireza, Teymoori Farshad, Eslamparast Tannaz, Sohrab Golbon, Hejazi Ehsan, Poustchi Hossein, Hekmatdoost Azita
机构信息
Student Research Committee, Department and Faculty of Nutrition Sciences and Food Technology, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Department of Clinical Nutrition and Dietetics, Faculty of Nutrition and Food Technology, National Nutrition and Food Technology, Research Institute, Shahid Beheshti University of Medical Sciences, No 7, West Arghavan St., Farahzadi Blvd., 1981619573, P.O.Box: 19395-4741, Tehran, Iran.
出版信息
Indian J Gastroenterol. 2019 Feb;38(1):55-60. doi: 10.1007/s12664-019-00937-8. Epub 2019 Feb 22.
BACKGROUND
It is known that diet plays a pivotal role in the pathogenesis and management of nonalcoholic fatty liver disease (NAFLD); however, the knowledge on the role of different food groups such as legumes is not enough.
METHODS
We designed this study to assess the relationship between legume intake and risk of NAFLD in framework of a case-control study among Tehrani adults. One hundred and ninety-six newly diagnosed patients with NAFLD and 803 controls were studied, and their dietary intake was assessed using a valid and reliable food frequency questionnaire. Conditional logistic regression was used to determine the odds ratio (OR) of NAFLD per increase of one serving/week dietary legumes, lentil, and beans adjusting for potential confounders.
RESULTS
In energy-adjusted model, greater intake of legumes, lentils, and beans was associated with a lower risk of NAFLD. These risk associations remained significant after adjusting for all known risk factors of NAFLD. OR of NAFLD in adjusted models for higher dietary intake of legumes, lentils, and beans were 0.73 (0.64-0.84), 0.61 (0.46-0.78), and 0.35 (0.17-0.74), respectively.
CONCLUSION
Our findings suggest that higher intake of total legumes (beans, lentils, and peas) was associated with lower risk of NAFLD.
背景
众所周知，饮食在非酒精性脂肪性肝病（NAFLD）的发病机制和管理中起着关键作用；然而，关于豆类等不同食物组作用的认识还不够充分。
方法
我们设计了这项研究，以在德黑兰成年人的病例对照研究框架内评估豆类摄入量与NAFLD风险之间的关系。研究了196例新诊断的NAFLD患者和803名对照，使用有效且可靠的食物频率问卷评估他们的饮食摄入量。采用条件逻辑回归来确定每增加一份/周的豆类、小扁豆和豆类饮食，在调整潜在混杂因素后NAFLD的比值比（OR）。
结果
在能量调整模型中，豆类、小扁豆和豆类的摄入量增加与NAFLD风险降低相关。在调整了所有已知的NAFLD风险因素后，这些风险关联仍然显著。在调整模型中，豆类、小扁豆和豆类摄入量较高时，NAFLD的OR分别为0.73（0.64 - 0.84）、0.61（0.46 - 0.78）和0.35（0.17 - 0.74）。
结论
我们的研究结果表明，豆类（豆类、小扁豆和豌豆）的摄入量较高与NAFLD风险较低相关。
Zotero 插件