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糖纳米载体作为药物递送的载体。

The glyconanoparticle as carrier for drug delivery.

机构信息

a Active Carbohydrate Research Institute , Chongqing Normal University , Chongqing , China.

b School of Chemistry and Environmental Engineering , Wuhan Institute of Technology , Wuhan , China.

出版信息

Drug Deliv. 2018 Nov;25(1):1840-1845. doi: 10.1080/10717544.2018.1519001.

DOI:10.1080/10717544.2018.1519001
PMID:30799659
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7011877/
Abstract

The glyconanoparticle (GlycoNP) has multiple effects and has important applications in drug delivery and bioimaging. It not only has the advantages of nano drug delivery system but also utilizes the characteristics of multivalent interaction of sugar, which greatly improves the targeting of drug delivery. Herein, the application of GlycoNP in drug delivery was analyzed and discussed, the solution to its problem was proposed, and its prospects were forecasted.

摘要

糖纳米粒子（GlycoNP）具有多种功效，在药物传递和生物成像方面有重要应用。它不仅具有纳米药物传递系统的优点，还利用了糖的多价相互作用的特性，极大地提高了药物传递的靶向性。本文分析和讨论了 GlycoNP 在药物传递方面的应用，提出了解决其问题的方法，并对其前景进行了预测。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fff5/7011877/025d90583b12/IDRD_A_1519001_F0005_C.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fff5/7011877/b8a91b2261c8/IDRD_A_1519001_F0001_C.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fff5/7011877/f4374786fb35/IDRD_A_1519001_F0002_C.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fff5/7011877/e980aeb5890c/IDRD_A_1519001_F0003_C.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fff5/7011877/b5933731a1b3/IDRD_A_1519001_F0004_C.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fff5/7011877/025d90583b12/IDRD_A_1519001_F0005_C.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fff5/7011877/b8a91b2261c8/IDRD_A_1519001_F0001_C.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fff5/7011877/f4374786fb35/IDRD_A_1519001_F0002_C.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fff5/7011877/e980aeb5890c/IDRD_A_1519001_F0003_C.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fff5/7011877/b5933731a1b3/IDRD_A_1519001_F0004_C.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fff5/7011877/025d90583b12/IDRD_A_1519001_F0005_C.jpg

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Triggerable Multivalent Glyconanoparticles for Probing Carbohydrate-Carbohydrate Interactions.用于探测碳水化合物-碳水化合物相互作用的可触发多价糖纳米颗粒
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Molecular recognition of glyconanoparticles by RCA and E. coli K88 - designing transports for targeted therapy.
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