• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

与HIV感染相关的虚弱:目前的解决办法是抗逆转录病毒药物:一种观点。

HIV Infection-Associated Frailty: The Solution for Now Is Antiretroviral Drugs: A Perspective.

作者信息

Klotz Stephen A, Bradley Nicole, Smith Shannon, Ahmad Nafees

机构信息

1 Division of Infectious Diseases, Department of Medicine, College of Medicine, University of Arizona, Tucson, AZ, USA.

2 Department of Immunobiology, College of Medicine, University of Arizona, Tucson, AZ, USA.

出版信息

J Int Assoc Provid AIDS Care. 2019 Jan-Dec;18:2325958219831045. doi: 10.1177/2325958219831045.

DOI:10.1177/2325958219831045
PMID:30803299
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6748472/
Abstract

This Perspective article provides a new view of frailty as it relates to HIV-1 infection. We discuss new findings and where our research is going.

摘要

这篇观点文章提供了一个与HIV-1感染相关的衰弱新视角。我们讨论了新发现以及我们的研究方向。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9aa1/6748472/f64189872520/10.1177_2325958219831045-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9aa1/6748472/f64189872520/10.1177_2325958219831045-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9aa1/6748472/f64189872520/10.1177_2325958219831045-fig1.jpg

相似文献

1
HIV Infection-Associated Frailty: The Solution for Now Is Antiretroviral Drugs: A Perspective.与HIV感染相关的虚弱:目前的解决办法是抗逆转录病毒药物:一种观点。
J Int Assoc Provid AIDS Care. 2019 Jan-Dec;18:2325958219831045. doi: 10.1177/2325958219831045.
2
The dynamic association between Frailty, CD4 and CD4/CD8 ratio in people aging with HIV.HIV 感染者衰老过程中衰弱、CD4 计数和 CD4/CD8 比值之间的动态关联。
PLoS One. 2019 Feb 14;14(2):e0212283. doi: 10.1371/journal.pone.0212283. eCollection 2019.
3
Influence of lifelong cumulative HIV viremia on long-term recovery of CD4+ cell count and CD4+/CD8+ ratio among patients on combination antiretroviral therapy.终生累积HIV病毒血症对接受联合抗逆转录病毒治疗患者CD4+细胞计数及CD4+/CD8+比值长期恢复的影响
AIDS. 2015 Mar 13;29(5):595-607. doi: 10.1097/QAD.0000000000000571.
4
Virologic and immunologic effects of adding maraviroc to suppressive antiretroviral therapy in individuals with suboptimal CD4+ T-cell recovery.在CD4+ T细胞恢复欠佳的个体中,将马拉维若添加至抗逆转录病毒抑制疗法的病毒学和免疫学效应
AIDS. 2015 Oct 23;29(16):2121-9. doi: 10.1097/QAD.0000000000000810.
5
Post-Treatment Controllers: Role in HIV "Cure" Research.治疗后病毒抑制者:在HIV“治愈”研究中的作用
Curr HIV/AIDS Rep. 2016 Feb;13(1):1-9. doi: 10.1007/s11904-016-0296-x.
6
Impact of hepatitis C virus coinfection on T-cell dynamics in long-term HIV-suppressors under combined antiretroviral therapy.丙型肝炎病毒合并感染对接受联合抗逆转录病毒治疗的长期HIV抑制者T细胞动态变化的影响。
AIDS. 2015 Jul 31;29(12):1505-10. doi: 10.1097/QAD.0000000000000650.
7
Persistent low viral load on antiretroviral therapy is associated with T cell-mediated control of HIV replication.抗逆转录病毒治疗期间持续低病毒载量与T细胞介导的HIV复制控制有关。
AIDS. 2005 Jan 3;19(1):25-33. doi: 10.1097/00002030-200501030-00003.
8
Role of antiretroviral therapies in mucocutaneous manifestations in HIV-infected children over a period of two decades.二十年间抗逆转录病毒疗法在HIV感染儿童皮肤黏膜表现中的作用
Br J Dermatol. 2005 Aug;153(2):382-9. doi: 10.1111/j.1365-2133.2005.06758.x.
9
The independent effect of drug resistance on T cell activation in HIV infection.耐药性对HIV感染中T细胞活化的独立影响。
AIDS. 2006 Mar 21;20(5):691-9. doi: 10.1097/01.aids.0000216369.30948.18.
10
T cell activation in HIV-seropositive Ugandans: differential associations with viral load, CD4+ T cell depletion, and coinfection.乌干达艾滋病毒血清阳性者的T细胞激活:与病毒载量、CD4 + T细胞耗竭及合并感染的不同关联
J Infect Dis. 2005 Mar 1;191(5):694-701. doi: 10.1086/427516. Epub 2005 Jan 31.

引用本文的文献

1
The Genie Is Out of the Bottle: Telemedicine Is More Effective Than Brick-and-Mortar Clinics in the Care of HIV-Infected Outpatients.精灵已从瓶中逃出:远程医疗在照顾HIV感染门诊患者方面比实体诊所更有效。
Am J Med. 2023 Apr;136(4):360-364. doi: 10.1016/j.amjmed.2022.11.012. Epub 2022 Dec 8.
2
The OATH Syndemic: opioids and other substances, aging, alcohol, tobacco, and HIV.OATH 综合征:阿片类药物和其他物质、老龄化、酒精、烟草和 HIV。
Curr Opin HIV AIDS. 2020 Jul;15(4):218-225. doi: 10.1097/COH.0000000000000635.
3
Predictors of Health Insurance Enrollment among HIV Positive Pregnant Women in Kenya: Potential for Adverse Selection and Implications for HIV Treatment and Prevention.

本文引用的文献

1
Reduction in terminally differentiated T cells in virologically controlled HIV-infected aging patients on long-term antiretroviral therapy.长期抗逆转录病毒治疗的病毒学控制的 HIV 感染老年患者中终末分化 T 细胞减少。
PLoS One. 2018 Jun 13;13(6):e0199101. doi: 10.1371/journal.pone.0199101. eCollection 2018.
2
Faces of Frailty in Aging with HIV Infection.感染HIV的老年人中的衰弱面容
Curr HIV/AIDS Rep. 2017 Feb;14(1):31-37. doi: 10.1007/s11904-017-0348-x.
3
Exergaming in Older People Living with HIV Improves Balance, Mobility and Ameliorates Some Aspects of Frailty.
肯尼亚艾滋病毒阳性孕妇参加健康保险的预测因素:不良选择的可能性及其对艾滋病毒治疗和预防的影响。
Int J Environ Res Public Health. 2020 Apr 22;17(8):2892. doi: 10.3390/ijerph17082892.
艾滋病毒感染者进行运动游戏可改善平衡能力、身体活动能力,并减轻虚弱的某些方面。
J Vis Exp. 2016 Oct 6(116):54275. doi: 10.3791/54275.
4
HCV monoinfection and HIV/HCV coinfection enhance T-cell immune senescence in injecting drug users early during infection.丙型肝炎病毒(HCV)单一感染和人类免疫缺陷病毒(HIV)/HCV合并感染会在感染早期增强注射吸毒者的T细胞免疫衰老。
Immun Ageing. 2016 Mar 31;13:10. doi: 10.1186/s12979-016-0065-0. eCollection 2016.
5
HIV-Related Frailty Is Not Characterized by Sarcopenia.与HIV相关的衰弱并非以肌肉减少症为特征。
J Int Assoc Provid AIDS Care. 2016 Mar-Apr;15(2):131-4. doi: 10.1177/2325957414553848. Epub 2014 Oct 15.
6
Measuring frailty in HIV-infected individuals. Identification of frail patients is the first step to amelioration and reversal of frailty.评估HIV感染者的虚弱状况。识别虚弱患者是改善和逆转虚弱状况的第一步。
J Vis Exp. 2013 Jul 24(77):50537. doi: 10.3791/50537.
7
Antiretroviral therapy protects against frailty in HIV-1 infection.抗逆转录病毒疗法可预防HIV-1感染导致的身体虚弱。
J Int Assoc Provid AIDS Care. 2013 Jan-Feb;12(1):62-6. doi: 10.1177/1545109712457241. Epub 2012 Oct 4.
8
Frailty in older adults: evidence for a phenotype.老年人的衰弱:一种表型的证据。
J Gerontol A Biol Sci Med Sci. 2001 Mar;56(3):M146-56. doi: 10.1093/gerona/56.3.m146.