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白藜芦醇给药的健康益处。

Health benefits of resveratrol administration.

作者信息

Galiniak Sabina, Aebisher David, Bartusik-Aebisher Dorota

机构信息

Faculty of Medicine, Rzeszów University, Rzeszów, Poland.

出版信息

Acta Biochim Pol. 2019 Feb 28;66(1):13-21. doi: 10.18388/abp.2018_2749.

Abstract

Resveratrol is a polyphenol that is abundant in grape skin and seeds. Food sources of resveratrol include wine, berries, and peanuts. This compound has many properties, including activity against glycation, oxidative stress, inflammation, neurodegeneration, several types of cancer, and aging. Because resveratrol is generally  welltolerated, it is believed to be a promising compound in preventing many diseases, such as diabetes and its complications. Unfortunately, this compound exhibits low bioavailability and solubility. The aim of this review is to summarize the latest information on the multiple effects of resveratrol on health and the benefits of its intake, based on in vitro and in vivo studies in animals and humans.

摘要

白藜芦醇是一种在葡萄皮和葡萄籽中含量丰富的多酚。白藜芦醇的食物来源包括葡萄酒、浆果和花生。这种化合物具有多种特性,包括抗糖化、氧化应激、炎症、神经退行性变、多种癌症以及衰老的活性。由于白藜芦醇通常耐受性良好,它被认为是预防许多疾病(如糖尿病及其并发症)的一种有前景的化合物。不幸的是,这种化合物的生物利用度和溶解度较低。本综述的目的是根据对动物和人类的体外和体内研究,总结关于白藜芦醇对健康的多种影响及其摄入益处的最新信息。

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