Higher Institute of Sport and Physical Education of Gafsa, Gafsa 2100, Tunisia.
Department of Physiology and Lung Function Testing, Faculty of Medicine Ibn-El-Jazzar, University of Sousse, Sousse 4000, Tunisia.
Int J Environ Res Public Health. 2019 Mar 1;16(5):751. doi: 10.3390/ijerph16050751.
Obesity is a chronic condition whose incidence is growing due to lack of exercise and frequent nutrition disorders. Childhood obesity has reached epidemic proportions worldwide. One of the best treatment methods is physical training. However, conflicting results have been reported regarding its clinical effectiveness. These contrasting findings may be due to the type and intensity of the adopted physical training program. Therefore, the purpose of the current study was to investigate the effect of an 8-week individualized physical training program on endothelial function, blood biomarkers and adipokine levels in obese children with and without metabolic syndrome (MS). One-hundred-and-twenty-two obese adolescents (71 obese without MS and 51 obese with MS) aged 14 ± 2 years were included in this study. The 8-week individualized training program decreased glucose, triglycerides, total cholesterol, low-density lipoprotein cholesterol and leptin in obese subjects with and without MS. However, adiponectin and endothelial-dependent vasodilatation increased in the follow-up study in both groups. Taken together, the findings suggest that individualized training program is an effective means for the treatment of obesity and MS in pediatric populations.
肥胖是一种慢性疾病，由于缺乏运动和经常出现营养失调，其发病率正在上升。儿童肥胖已在全球范围内达到流行程度。最好的治疗方法之一是体育锻炼。然而，关于其临床效果的报道结果却相互矛盾。这些相互矛盾的结果可能是由于所采用的体育训练计划的类型和强度不同。因此，本研究的目的是调查 8 周个体化体育训练计划对伴有和不伴有代谢综合征（MS）的肥胖儿童的内皮功能、血液生物标志物和脂肪因子水平的影响。本研究纳入了 122 名年龄在 14 ± 2 岁的肥胖青少年（71 名肥胖无 MS 和 51 名肥胖伴 MS）。8 周的个体化训练计划降低了伴有和不伴有 MS 的肥胖患者的血糖、甘油三酯、总胆固醇、低密度脂蛋白胆固醇和瘦素。然而，在随访研究中，两组的脂联素和内皮依赖性血管舒张均增加。总之，这些发现表明个体化训练计划是治疗儿科肥胖和 MS 的有效手段。
