BABA Center, Children's Hospital, HUS Medical Imaging Center, Department of Clinical Neurophysiology, Helsinki University Hospital, Helsinki, Finland.
Clinicum, University of Helsinki, Helsinki, Finland.
Sci Data. 2019 Mar 5;6:190039. doi: 10.1038/sdata.2019.39.
Neonatal seizures are a common emergency in the neonatal intensive care unit (NICU). There are many questions yet to be answered regarding the temporal/spatial characteristics of seizures from different pathologies, response to medication, effects on neurodevelopment and optimal detection. The dataset presented in this descriptor contains EEG recordings from human neonates, the visual interpretation of the EEG by the human experts, supporting clinical data and codes to assist access. Multi-channel EEG was recorded from 79 term neonates admitted to the NICU at the Helsinki University Hospital. The median recording duration was 74 min (IQR: 64 to 96 min). The presence of seizures in the EEGs was annotated independently by three experts. An average of 460 seizures were annotated per expert in the dataset; 39 neonates had seizures and 22 were seizure free, by consensus. The dataset can be used as a reference set of neonatal seizures, in studies of inter-observer agreement and for the development of automated methods of seizure detection and other EEG analyses.
新生儿癫痫发作是新生儿重症监护病房（NICU）中的常见急症。关于不同病理的癫痫发作的时间/空间特征、对药物的反应、对神经发育的影响以及最佳检测方法，仍有许多问题有待解答。本描述符中提供的数据集包含来自人类新生儿的脑电图记录、人类专家对脑电图的视觉解释、支持临床数据和代码以辅助访问。从赫尔辛基大学医院的 NICU 收治的 79 名足月新生儿中记录了多通道脑电图。记录的中位持续时间为 74 分钟（IQR：64 至 96 分钟）。癫痫发作的存在由三位专家独立注释。每位专家在数据集中平均注释了 460 次癫痫发作；通过共识，39 名新生儿有癫痫发作，22 名新生儿无癫痫发作。该数据集可作为新生儿癫痫发作的参考集，用于研究观察者间的一致性，并开发用于癫痫发作检测和其他 EEG 分析的自动方法。
