Chemical Characterization, Antioxidant, Cytotoxic and Microbiological Activities of the Essential Oil of Leaf of (Hemsl) A. Gray (Asteraceae).

The present study aimed to evaluate the chemical composition, antioxidant potential, and the cytotoxic and antimicrobial activity of the essential oil of the plant species (Hemsl) A. Gray. The essential oil obtained was used to identify the chemical compounds present through the techniques of GC-MS and NMR. The antioxidant potential was calculated by the sequestration method of 2,2-diphenyl-1-picrylhydrazyl. For cytotoxic activity, the larval mortality of was evaluated. The main chemical constituents identified are pinene (9.9%), Limonene (5.40%), --ocimene (4.02%), -cymen-8-ol (3.0%), Piperitone (11.72%), -nerolidol (3.78%) and Spathulenol (10.8%). In the evaluation of the antimicrobial activity, bacterial strains of , and were used. The results showed that the bacterium were more susceptible to the presence of the essential oil, presenting minimal inhibitory concentration at the concentrations that were exposed. The essential oil presented antioxidant activity of 54.6% at the concentration of 5 mg·mL and provided a CI of 4.30. It was observed that the essential oil of this species was highly toxic against lavas, as its cytotoxic activity showed an LC of 3.11. Thus, it is concluded that oils are effective in inhibiting bacterial growth and reducing oxidative stress.