Jiang Chen, Xu Yan, Sharma Stuti, Zhang Lei, Wang Huan, Song Jun, Qian Wei, Bai Tao, Hou Xiaohua
Division of Gastroenterology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
J Neurogastroenterol Motil. 2019 Apr 30;25(2):233-240. doi: 10.5056/jnm18028.
BACKGROUND/AIMS: The role of psychosocial factors on irritable bowel syndrome (IBS) in adolescents is incompletely understood. The aim of this study is to investigate the association between the psychosocial factors and the risk of developing IBS in college freshmen.
A cross-sectional survey was conducted in a randomly selected freshmen population in Wuhan China (n = 2449). Questionnaire evaluated demographics and psychosocial risks. The population was divided into 3 groups: non-discomfort, chronic abdominal discomfort and IBS. The association between the development of IBS and psychosocial factors was analyzed by ordinal and multiple logistic regression analysis.
A total of 2053 (83.8%) completed this survey (mean age, 18.2 ± 0.9 years; female, 35.6%). Among them, 82 (4.0%) fulfilled the Rome III criteria for IBS. Female (odds ratio [OR], 3.31; 95% confidence interval [CI], 2.47-4.45), experience of abuse (OR, 2.44; 95% CI, 1.10-5.56), and suicidal intention (OR, 2.17; 95% CI, 1.15-4.17) were more likely to have IBS. Compared with chronic abdominal discomfort, however, depression (OR, 5.55; 95% CI, 1.36-22.71) was the only dependent risk factor for IBS.
The prevalence of IBS in college freshmen is 4.0%, and to the freshmen, psychosocial factors such as experience of abuse, depression, and suicidal intention were associated with high risk of developing IBS.
背景/目的：心理社会因素在青少年肠易激综合征（IBS）中的作用尚未完全明确。本研究旨在调查心理社会因素与大学新生患IBS风险之间的关联。
对中国武汉随机抽取的大一新生群体（n = 2449）进行横断面调查。通过问卷评估人口统计学和心理社会风险因素。将该群体分为3组：无不适、慢性腹部不适和IBS。采用有序和多元逻辑回归分析IBS发病与心理社会因素之间的关联。
共有2053名（83.8%）学生完成了调查（平均年龄18.2±0.9岁；女性占35.6%）。其中，82名（4.0%）符合IBS的罗马III标准。女性（优势比[OR]，3.31；95%置信区间[CI]，2.47 - 4.45）、有虐待经历（OR，2.44；95% CI，1.10 - 5.56）和有自杀意图（OR，2.17；95% CI，1.15 - 4.17）者患IBS的可能性更大。然而，与慢性腹部不适相比，抑郁（OR，5.55；95% CI，1.36 - 22.71）是IBS唯一的相关风险因素。
大学新生中IBS的患病率为4.0%，对于新生而言，虐待经历、抑郁和自杀意图等心理社会因素与患IBS的高风险相关。
