用于连续流动反应的低成本3D打印设备。

Neumaier Jochen M, Madani Amiera, Klein Thomas, Ziegler Thomas

Institute of Organic Chemistry, University of Tübingen, Auf der Morgenstelle 18, 72076 Tübingen, Germany.

Beilstein J Org Chem. 2019 Feb 26;15:558-566. doi: 10.3762/bjoc.15.50. eCollection 2019.

This article describes the development and manufacturing of lab equipment, which is needed for the use in flow chemistry. We developed a rack of four syringe pumps controlled by one Arduino computer, which can be manufactured with a commonly available 3D printer and readily available parts. Also, we printed various flow reactor cells, which are fully customizable for each individual reaction. With this equipment we performed some multistep glycosylation reactions, where multiple 3D-printed flow reactors were used in series.

本文介绍了用于流动化学的实验室设备的开发与制造。我们开发了一种由一台Arduino计算机控制的四台注射泵组成的架子，它可以用普通的3D打印机和现成的零件制造。此外，我们打印了各种流动反应器单元，每个反应都可以完全定制。利用该设备，我们进行了一些多步糖基化反应，其中多个3D打印的流动反应器串联使用。