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绿色纳米技术:植物制剂研究进展

Green Nanotechnology: Advancement in Phytoformulation Research.

作者信息

Verma Ajay, Gautam Surya P, Bansal Kuldeep K, Prabhakar Neeraj, Rosenholm Jessica M

机构信息

Pharmaceutical Sciences Laboratory, Faculty of Science and Engineering, Åbo Akademi University, 20520 Turku, Finland.

CT Institute of Pharmaceutical Sciences, Jalandhar 144020, India.

出版信息

Medicines (Basel). 2019 Mar 14;6(1):39. doi: 10.3390/medicines6010039.

Abstract

The ultimate goal of any scientific development is to increase well-being and human health. Novel strategies are required for the achievement of safe and effective therapeutic treatments beyond the conventional ones, and society needs new requirements for new technologies, moving towards clean and green technology development. Green nanotechnology is a branch of green technology that utilizes the concepts of green chemistry and green engineering. It reduces the use of energy and fuel by using less material and renewable inputs wherever possible. Green nanotechnology, in phytoformulations, significantly contributes to environmental sustainability through the production of nanomaterials and nanoproducts, without causing harm to human health or the environment. The rationale behind the utilization of plants in nanoparticle formulations is that they are easily available and possess a broad variability of metabolites, such as vitamins, antioxidants, and nucleotides. For instance, gold (Au) nanoparticles have attracted substantial attention for their controllable size, shape, and surface properties. A variety of copper (Cu) and copper oxide (CuO) nanoparticles have also been synthesized from plant extracts. Titanium dioxide and zinc oxide nanoparticles are also important metal oxide nanomaterials that have been synthesized from a number of plant extracts. International and domestic laws, government and private-party programs, regulations and policies are being carefully reviewed and revised to increase their utility and nurture these nanoscale materials for commercialization. Inspiring debates and government initiatives are required to promote the sustainable use of nanoscale products. In this review, we will discuss the potential of the utilization of plant extracts in the advancement of nanotechnology.

摘要

任何科学发展的最终目标都是增进人类福祉和健康。要实现超越传统方法的安全有效的治疗手段,需要新的策略,社会也需要对新技术提出新要求,朝着清洁和绿色技术发展迈进。绿色纳米技术是绿色技术的一个分支,它运用了绿色化学和绿色工程的理念。只要有可能,它就通过减少材料使用和采用可再生原料来降低能源和燃料的消耗。在植物制剂中,绿色纳米技术通过生产纳米材料和纳米产品,在不对人类健康和环境造成危害的情况下,对环境可持续性做出了重大贡献。在纳米颗粒制剂中使用植物的基本原理是它们易于获取,并且含有多种代谢物,如维生素、抗氧化剂和核苷酸。例如,金(Au)纳米颗粒因其可控制的尺寸、形状和表面性质而备受关注。多种铜(Cu)和氧化铜(CuO)纳米颗粒也已从植物提取物中合成。二氧化钛和氧化锌纳米颗粒也是重要的金属氧化物纳米材料,它们已从多种植物提取物中合成。国际和国内法律、政府及私人项目、法规和政策正在被仔细审查和修订,以提高其效用并培育这些纳米级材料用于商业化。需要开展鼓舞人心的辩论和政府倡议来促进纳米级产品的可持续利用。在本综述中,我们将讨论利用植物提取物推动纳米技术发展的潜力。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dd95/6473607/6727757141a8/medicines-06-00039-g001.jpg

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