Department of Health Services Management, School of Health Management and Information Sciences, Iran University of Medical Sciences, Tehran, Iran.
Health Technology Assessment, School of Health Management and Information Science, Iran University of Medical sciences, Tehran, Iran.
J Anesth. 2019 Jun;33(3):441-453. doi: 10.1007/s00540-019-02629-1. Epub 2019 Mar 20.
Noninvasive hemoglobin (Hb)-monitoring devices are new inventions in pulse oximeter systems that show hemoglobin levels continuously. The aim of this systematic review and meta-analysis was to evaluate the accuracy and precision of noninvasive versus standard central laboratory Hb measurements in the operating room. We systematically searched multiple databases. Then, for the quality assessment of studies, we modified QUADAS-2 in the Revman 5.3 software. The GRADE approach was used to measure the quality of evidence (Grading of Recommendations Assessment, Development, and Evaluation). Data were analyzed using the meta-analysis method (random effect model) using STATA 11 software. A total of 28 studies on 2000 participants were included in the meta-analysis. Meta-analysis results of mean differences between noninvasive and the central laboratory Hb measurements in overall pooled random effects were - 0.27 (95% LoA (0.44, - 0.10); P value < 0.05). According to this meta-analysis, noninvasive hemoglobin measurement has acceptable accuracy in comparison with the standard invasive method.
非侵入式血红蛋白（Hb）监测设备是脉搏血氧仪系统中的新发明，可以连续显示血红蛋白水平。本系统评价和荟萃分析的目的是评估手术室中与非侵入式与标准中心实验室 Hb 测量的准确性和精密度。我们系统地搜索了多个数据库。然后，为了评估研究的质量，我们在 Revman 5.3 软件中修改了 QUADAS-2。使用 GRADE 方法（推荐评估、制定和评估分级）来衡量证据质量。使用 STATA 11 软件采用荟萃分析方法（随机效应模型）进行数据分析。共有 28 项涉及 2000 名参与者的研究纳入荟萃分析。总体随机效应荟萃分析结果显示，非侵入式与中心实验室 Hb 测量值之间的平均差异为 -0.27（95% LoA（0.44，-0.10）；P 值 <0.05）。根据这项荟萃分析，与标准侵入性方法相比，非侵入式血红蛋白测量具有可接受的准确性。
